海水鱼体中的二噁英类化合物分析  

Determination of PCDDs/PCDFs in Fish by Isotope Dilution HRGC/HRMS

作　　者：姜杰[1] 张建清[1] 蒋友胜[1] 周健[1] 张红宇[1] 邓辉萍[1] 陈裕华[1] 

机构地区：[1]深圳市疾病预防控制中心,广东518020

出　　处：《中国预防医学杂志》2004年第6期437-440,共4页Chinese Preventive Medicine

基　　金：广东省卫生厅科研基金资助(A2002110)

摘　　要：目的对海水鱼体内二英检测方法的研究。方法参照美国EPA1613方法,采用索式抽提和自动纯化系统等仪器对鱼体中的二英组分进行纯化和富集、用同位素稀释气相色谱与高分辨质谱联用-多离子检测方法检测。结果该方法的检测限为0001pg/g～0176pg/g,仪器检测限为65fg～1579fg,同位素标准物的回收率分布于7081%～8733%之间,17种2,3,7,8-氯取代的二英类化合物在鱼体中均可检测出,总TEQ值为1117pg/g。结论本实验室方法可以准确检测样品中二英类化合物,所检鱼体中含有二英化合物,有必要做更多样品,对其污染情况做出评价。Objective 2,3,7,8-Chlorine-Substituted Dibenzo-p-dioxins and furans in fish were determined by HRGC/HRMS Methods According to EPA1613,Dibenzo-p-Dioxins and Dibenzo-Furans were extracted from fish by Soxhlet extraction, cleaned up by FMS and quantified by HRGC/HRMS-MID, using isotope dilution methodology Results The method detection was 0 001 pg/g～0 176 pg/g,The instrument detection was 6 5 fg～157 9 fg,The recovery rate was 70 81%～87 33%,seventeen congeners of 2,3,7,8-Chlorine-Substiturted Dibenzo-p-dioxins and furans PCDDs/PCDFs were measured in fish, Total Toxicity Equivalency Quantity (TEQ) of the fish sample was 1 117pg/g Conclusions PCDFs/PCDDs in the fish sample can be measured accurately by this method ,more fish samples need to be measured to evaluate the contamination of fish samples in China

关 键 词：二噁英类 鱼类 HRGC/HRMS 同位素 自动纯化系统 

分 类 号：X503.2[环境科学与工程—环境工程]