偏最小二乘法-近红外漫反射光谱法快速分析西米替丁粉末药品  

Use of PLS and near-infrared spectroscopy in analyzing Cimetidine power rapidly

作　　者：刘革[1] 窦英[2] 汤真 刘福强[1] 刘名扬 任玉林[2] 

机构地区：[1]解放军208医院药剂科,长春130036 [2]吉林大学化学学院,长春130023

出　　处：《生命科学仪器》2004年第6期33-35,共3页Life Science Instruments

摘　　要：研究了用偏最小二乘法(PLS)同近红外漫反射光谱结合,对西米替丁粉末药品进行快速定量分析的方法,建立了最佳的数学校正模型。讨论了波长间隔和主成分数对PLS定量预测能力的影响,预测了未知样品,结果令人满意。The application of PLS and near-infrared spectroscopy for Cimetidine power rapid quantitative analysis were investigated and the best mathematic calibration models were built. The effects of the interval of wavelength and the numbers of principal component on the prediction ability of PLS were discussed and the prediction set was predicted. The predicted results were reliable.

关 键 词：西米替丁 药品 近红外漫反射光谱法 PLS 粉末 偏最小二乘法 影响 数学 分数 学校 

分 类 号：TH814.92[机械工程—仪器科学与技术] R951[机械工程—精密仪器及机械]