^252Cf裂变中子照射洋葱干种子后根尖细胞内微核诱发率的研究  

Study of micronucleus induction in the root-tip cells of onion seedlings after irradiation as dry dormant seeds by 252Cf fission neutrons

作　　者：张文艺[1] 焦玲[1] 星正治[2] 

机构地区：[1]中国医学科学院中国协和医科大学放射医学研究所,天津300192 [2]广岛大学原爆放射线医科学研究所

出　　处：《辐射研究与辐射工艺学报》2005年第1期15-18,共4页Journal of Radiation Research and Radiation Processing

摘　　要：用252Cf 中子 γ 射线混合照射观察了不同剂量对洋葱根尖细胞微核诱发率的差异,研究252Cf 裂变中子 的相对生物效应(Relative biological effectivencess, RBE)。结果表明,单位剂量 252Cf 中子 γ 射线混合照射的微 核诱发率为(1.84±0.10)%Gy-1,而归因于单位剂量 252Cf 裂变中子的微核诱发率为(2.74±0.15)%Gy-1;单 位剂量60 Co γ 射线的微核诱发率为(0.022±0.002)%Gy-1。252Cf 中子 γ 射线混合照射的 RBE 值为 84±9,252Cf 裂变中子的 RBE 值为 124±13。单位剂量 252Cf 中子 γ 射线混合照射在 Allium cepa 洋葱种子根尖细胞内的微 核诱发率约为 60Co γ 射线的 84 倍,中子照射所致 DNA 损伤的修复效率,可能不同于由 γ 射线照射所致 DNA 损伤的修复效率。The work is for a better understanding of relative biological effectiveness (RBE) of 252Cf fission neutrons. The frequency of micronuclei induced in the root-tip cells of onion seedlings after irradiation as dry dormant seeds by unit dose of 252Cf neutron-γ mixed irradiation is different from that by 60Co γ-ray irradiation. The frequency of micronuclei induced by unit dose of 252Cf neutron-γ mixed irradiation and 60Co γ-ray irradiation are 1.84±0.10 and 0.022±0.002 (%Gy-1), respectively; and the frequency of micronuclei induced by unit dose of 252Cf fission neutrons is 2.74±0.15 (%Gy-1). The RBE values for 252Cf neutron-γ mixed irradiation and 252Cf fission neutrons are 84±9 and 124±13, respectively. The frequency of micronuclei induced in the root-tip cells of Allium cepa onion seedlings irradiated as dry dormant seeds by unit dose of 252Cf neutron-γ mixed irradiation is about 84 times as that by 60Co γ-ray irradiation. The findings suggested that repair efficiency of DNA damage induced by neutrons might be different from that by γ-ray.

关 键 词：^252Cf 中子 微核 洋葱种子 相对生物效应 

分 类 号：Q691.6[生物学—生物物理学] R144.1[医药卫生—公共卫生与预防医学]