盐酸氨溴索口服溶液改善COPD患者咳痰困难的疗效  

An observation on expectorant effect of ambroxol hydrochloride oral solution in patients with COPD

作　　者：宋永辉[1] 王艳红[2] 

机构地区：[1]河北保定解放军第252医院呼吸科,071000 [2]河北省荣军医院

出　　处：《实用心脑肺血管病杂志》2004年第6期335-337,共3页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

摘　　要：目的 观察盐酸氨溴索口服溶液对慢性阻塞性肺部疾病(COPD)患者咳痰困难的临床疗效。 方法 96例COPD伴有咳痰困难患者随机分成2组,治疗组给予盐酸氨溴索口服溶液,对照组给予必嗽平,两组同时给 予常规抗生素,观察给药前后患者咳嗽、咳痰的轻重程度,比较患者住院病程的长短,并记录不良反应。结果 盐酸氨溴索组总有效率100％,平均住院时间为8.9天,对照组有效率不足84％,平均住院时间12.8天,两组之间 疗效有显著性差异,盐酸氨溴索组副反应轻微且发生率低。 结论 盐酸氨溴索口服溶液在改善COPD患者咳 嗽、咳痰方面明显优于对照组,可提高抗生素疗效,缩短患者住院时间,有疗效佳、起效快、副作用小等优点。Objective To observe the expectorant effect of ambroxol hydrochloride oral solution in patients with COPD. Methods There were 96 patients with COPD being hard to expectorate sputum,they were divided randomly into two groups: the patients in treaded group were given ambroxol hydrochloride oral solution, control group given bromhex-ine. The expectorant and side effect were compared with each other before and after treatment in the two groups. Results The effective rate was 100% ,in the treated group with an average hospitalization days of 8. 9 days, moreover they were < 84% and 12.8 days in the control. The side effects of ambroxol hydrochloride were mild and uncommon. Conclusion It should have a good expectorant effect that ambroxol hydrochloride oral solution was used to treat the patients with COPD being hard to expectorate sputum.

关 键 词：盐酸氨溴索 咳痰 COPD患者 口服溶液 住院时间 对照组 疗效 咳嗽 观察 抗生素 

分 类 号：R563[医药卫生—呼吸系统] R722[医药卫生—内科学]