亚铜催化法^(131)I标记间碘苄胍的研究  

Study on Method of Cuprous Catalysis for ^(131)I Marking MIBG

作　　者：李勇[1] 李红全 

机构地区：[1]贵州民族学院化学与环境科学学院,贵州贵阳550004 [2]西南核物理与化学研究所,四川绵阳621000

出　　处：《西南师范大学学报（自然科学版）》2005年第1期101-103,共3页Journal of Southwest China Normal University(Natural Science Edition)

摘　　要：采用亚铜做催化剂, 研究了131I标记间碘苄胍的方法, 即是沸水浴温度, 标记时间 15 min, 用铜量 2. 5μg和抗坏血酸量5. 0 mg; 纸层析法分析标记物, 标记率大于97%. 此标记方法不需要进一步的分离, 具有简单、快速的特点.A new method for (^(131)I) labeled metaiodobenzyl guanidine (MIBG) was studied using cuprous as catalyst. That is the boiling temperature within 15 minute and 2.5 μg of cuprous, 5.0 mg of ascorbic acid; A labeled efficiency more than 97% is obtained by paper chromatography. The method has characteristic of simple and fast, and it has no need for further separation.

关 键 词：胍乙啶 ^131I-间碘苄胍 亚铜催化 纸层析法 标记 

分 类 号：O655[理学—分析化学]