粘液素对草酸钙晶体生长的影响  

Investigation on growth of calcium oxalate crystal in the presence of mucin

作　　者：陈德志[1] 欧阳健明[1] 

机构地区：[1]暨南大学生物矿化与结石病防治研究所,广东广州510632

出　　处：《化学研究与应用》2005年第1期61-63,共3页Chemical Research and Application

基　　金：广东省重点攻关项目(C31401);国家自然科学基金重点项目(20031010);广东省自然科学基金重点项目(013202);广东省"千百十工程"优秀人才培养基金 (Q0 2 0 60 )

摘　　要：The influence of mucin on the growth of calcium oxalate crystals was investigated by means of scanning electron microscopy and X-ray diffraction. In the control systems without mucin, calcium oxalate monhydrate(COM) crystals were the polymorphs without uniforn shape, and the (010) crystal face of COM was preferential grown.However,in the presence of mucin both the size and number of COM crystals were decreased, and the intensity of the diffraction peak of (101) face was strengthened in the debt of (010) face of COM crystals. It indicated that mucin can inhibit both the nucleation and growth of COM crystals, so mucin can prevent the formation of CaOxa stones.The influence of mucin on the growth of calcium oxalate crystals was investigated by means of scanning electron microscopy and X-ray diffraction. In the control systems without mucin, calcium oxalate monhydrate(COM) crystals were the polymorphs without uniforn shape, and the (010) crystal face of COM was preferential grown.However,in the presence of mucin both the size and number of COM crystals were decreased, and the intensity of the diffraction peak of (101) face was strengthened in the debt of (010) face of COM crystals. It indicated that mucin can inhibit both the nucleation and growth of COM crystals, so mucin can prevent the formation of CaOxa stones.

关 键 词：草酸钙 粘液素 尿结石 

分 类 号：O614.231[理学—无机化学] R3[理学—化学]