腺嘌呤在非4℃条件下保存血液代谢特点研究  

Study on the metabolic character of adenine on stored whole blood at non-4℃

作　　者：韩玮[1] 骆群[1] 刘景汉[1] 王青梅[1] 

机构地区：[1]解放军总医院输血科,北京100853

出　　处：《临床输血与检验》2001年第4期4-5,8,共3页Journal of Clinical Transfusion and Laboratory Medicine

基　　金：全军医药卫生"九.五"重点攻关课题 (编号 :98Z0 86)

摘　　要：目的　研究非 4℃条件下血液保存过程中腺嘌呤的代谢特点。　方法　以 CPD和 CPDA全血为研究标本 ,于2 5℃条件下 ,分别取保存不同时间的血液测定 ATP和腺嘌呤。　结果　腺嘌呤在保存初期即消耗殆尽 ,与 ATP升高相对应。　结论　腺嘌呤在保存初期即参与 ATP的合成代谢 ,对提高 ATP水平。Objective To research the metabolic character of adenine of preserved whole blood under non 4℃ condition. Methods We determined ATP and adenine of CPD and CPDA whole blood under 25℃ from 0 d to 6 d. Results The adenine runed out at the beginning of storage while ATP increased significantly. Conclusion At the beginning of storage, adenine involved in the ATP synthesization, and it plays an important role on prolonging the whole blood storage.

关 键 词：腺嘌呤 ATP 血液保存 保存血 初期 代谢特点 不同时间 标本 全血 水平 

分 类 号：R457[医药卫生—治疗学] R446[医药卫生—临床医学]