参附注射液在小儿特发性血小板减少性紫癜中的临床应用  

Clinical application of Ginseng and Radix aconiti praeparata injection in children with idiopathic thrombocytopenic purpura

作　　者：杜长江[1] 王二惠[1] 杨小巍[1] 谢雪兰[1] 柏金秀[1] 安小肖[1] 闫俊平[1] 张淑娟[1] 

机构地区：[1]河北职工医学院附属医院儿科

出　　处：《中国当代儿科杂志》1999年第2期87-88,共2页Chinese Journal of Contemporary Pediatrics

基　　金：河北省科委计划内项目

摘　　要：应用参附注射液替代或部分替代肾上腺皮质激素治疗小儿特发性血小板减少性紫癜（ＩＴＰ），开辟新的治疗途径。方法采用中西医结合的方法，观察参附注射液治疗３１例ＩＴＰ患儿的疗效，并与同期用激素治疗的２７例及对症治疗的３１例ＩＴＰ患儿进行比较。结果参附注射液治疗组，在治疗２５ｄ时血小板回升和ＣＤ４＋／ＣＤ８＋回升明显高于激素组及对症治疗组（Ｐ＜０．０１），且无副作用。结论应用参附注射液或加用肾上腺皮质激素治疗ＩＴＰ优于肾上腺皮质激素，值得推广。Objective To search for a new therapy for idiopathic thormbocytopenic purpura(ITP) in children, cortisone therapy was replaced by Ginseng and Radix aconiti praeparata injection (GRA). Methods Chinese traditional medicine combined with Western medicine was adopted to observe the effect of Ginseng and Radix aconiti praeparata injection on 31 cases of ITP. 27 randomly selected cases treated with cortisone were compared with the 31 cases without special treatment at the same time. Results Obvious increase in the Platelet and CD 4 +/CD 8 + was found in the treatment groups of GRA or GRA plus cortisone as compared with the cortisone treatment or control group(both P <0.01).Conclusions GRA and GRA plus cortisone treatment are better than cortisone in the treatment of ITP and its clinical application is desirable.

关 键 词：对症治疗 参附注射液 临床应用 ITP 特发性血小板减少性紫癜 肾上腺皮质激素 患儿 替代 目的 方法 

分 类 号：R554.6[医药卫生—血液循环系统疾病] R735.7[医药卫生—内科学]