急性心肌梗死发病与入院时C-反应蛋白水平的关系  

Relation between C-reactive protein levels on admission and pattern of acute myocardial infarction onset

作　　者：战晓芃[1] 石耀辉[1] 孙秀珍[1] 陈国俊[1] 

机构地区：[1]黑龙江省医院,150036

出　　处：《中国急救医学》2001年第1期20-21,共2页Chinese Journal of Critical Care Medicine

摘　　要：目的　为了明确入院时C -反应蛋白 (CRP)水平与急性心肌梗死 (AMI)发病间的关系。方法　 96例AMI患者根据入院 6小时内测得的CRP水平将其分为 3组 ,C组 5 3例 (CRP 0 0 0 2～ 0 0 0 6g/L) ;L组 2 5例 (CRP <0 0 2 6g/L) ;H组 18例(CRP≥ 0 0 2 6g/L)。所有入选患者入院时立即给予冠状动脉造影术 ,CRP测定采用散射速率比浊法。结果　入院时CRP升高较CRP不高的患者在AMI发病前不稳定型心绞痛发病率高 (P <0 0 5 ) ,且在AMI发病时身体活动处于较低水平 (P <0 0 0 1) ,与梗死范围及受累血管数目无关。Objective To examine the relation between CRP levels on admission and the onset pattern of AMI to estimate the contribution of inflammation to the pathogenesis of AMI.Methods Total 96 patients with AMI according to their CRP levels within the first 6 hours after the onset of AMI are divided into three groups,group C,n=53(CRP 0 002～0 006 g/L);group L,n=25(CRP<0.026 g/L);group H,n=18(CRP≥0.026 g/L).Coronary angiography was performed immediately after admission in all patients.CRP levels were measured by scatter rate turbidity comparison.Results Patients with elevated CRP levels were more likely to have had a history of unstable angina and symptom onset at lower level of physical activity than those without elevated CRP levels ( P <0.05, P <0.001).Conclusion The pathogenesis of AMI may be influenced by preexisting inflammatory activity. [

关 键 词：急性心肌梗塞 C-反应蛋白 不稳定型心绞痛 

分 类 号：R542.22[医药卫生—心血管疾病]