山东青岛市和贵州安顺市原发性痛风患者发病特征及致病因素比较  

Comparison of episode characteristics and etiological factors of patients with primary gout in Qingdao of Shandong province and Anshun of Guizhou province

作　　者：刘斌[1] 刘文曲[2] 曲世平[1] 邢倩[1] 吴宁[1] 

机构地区：[1]青岛市市立医院免疫风湿科,山东省青岛市266011 [2]贵州省安顺市人民医院内科,贵州省安顺市561000

出　　处：《中国临床康复》2005年第3期44-45,共2页Chinese Journal of Clinical Rehabilitation

摘　　要：目的:痛风在中国发病率呈上升趋势,探讨青岛市和安顺市原发性痛风患者的表现特点及致病诱因的差异。方法:2003-07/2004-04,收集山东省青岛市市立医院免疫风湿科和贵州省安顺市人民医院78例痛风患者,青岛组42例,安顺组36例。对比两地痛风患者临床资料特点及发病诱因,进行统计分析。结果:两地痛风平均发病年龄差异无显著性意义,安顺患者确诊时平均病程较青岛患者长,差异有显著性意义(P<0.01);临床表现两地首发部位均以第一跖趾关节为主,实验室检查及伴发病两地差异无显著性意义。青岛26.2%患者X射线片显示典型的穿凿样变,而安顺患者为50%,差异有显著性意义(P<0.05)。青岛54.8%患者以海鲜和/或啤酒为主要发病诱因,安顺以火锅和/或白酒为主(52.7%)。结论:地理、饮食习惯对临床表现、生化检查、伴发病无明显影响,但饮食习惯不同可造成发病诱因不同。AIM:The incidence rate of gout in China shows an increasing tendency.This study investigates the differences of manifestation feature and etiological factors of patients with primary gout in Qingdao and Anshun cities. METHODS:Clinical data of 78 patients with gout were collected from the Department of Immunology and Rheumatology of Qingdao Municipal Hospital(n=42) and Anshun Municipal People's Hospital(n=36) from July 2003 to April 2004.The features of clinical manifestation and etiological factors were compared between the patients with gout in Qingdao and Anshun for statistical analysis. RESULTS:No significant difference was found in the mean age of onset between Qingdao and Anshun, whereas the average disease duration at final diagnosis of onset in Anshun was significant longer than in Qingdao(P< 0.01).In the initial attacks, the first metatarsophalangeal joint was mainly affected in both areas.There were no significant difference in laboratory test and associated disorders.The results of X-ray showed that classical “punched out”appearance was found in 26.2%of the patients in Qingdao but 50%in Anshun, and there was significant difference(P< 0.05).Major etiological factors were seafood and/or beer in Qingdao(54.8%),but chafing dish and/or white wine in Anshun(52.7%). CONCLUSION:Geography and eating habits have no influence on clinical manifestation, biochemical test and associated disorders,but the different eating habits cause the difference in etiological factors.

关 键 词：痛风 因素分析 统计学 饮食习惯 地理位置 

分 类 号：R593.2[医药卫生—内科学]