2型糖尿病合并冠心病患者冠状动脉受累程度与病程的关系  

Relationship between involved coronary artery and disease course in patients with type 2 diabetes mellitus and coronary heart disease

作　　者：李民强[1] 王德峰[2] 王海涛[1] 白宝银[1] 牛红霞[1] 

机构地区：[1]河北工程学院附属医院心脏中心,河北省邯郸市056029 [2]河北工程学院附属医院内分泌科,河北省邯郸市056029

出　　处：《中国临床康复》2005年第3期100-101,共2页Chinese Journal of Clinical Rehabilitation

摘　　要：目的:探讨不同患病年限糖尿病合并冠心病患者冠状动脉造影的特点。方法:2002-06/2004-02河北工程学院附属医院心脏中心行冠状动脉造影患者122例。符合标准的冠心病患者92例,其中非糖尿病患者42例(非糖尿病组),患2型糖尿病5年患者22例(糖尿病5年组);患2型糖尿病>5年患者28例(糖尿病>5年组)。分析比较3组之间的临床资料和冠状动脉病变特点。结果:糖尿病5年组病变血管数量分布上以及病变程度、形态与无糖尿病组比较,差异均无显著性意义(P>0.05)。糖尿病>5年组患者冠状动脉发生单支病变、局限性病变、3支病变以及弥漫病变、闭塞病变犤4例(14%),12例(43%),2例(7%),9例(32%),8例(29%)犦情况与无糖尿病组犤14例(33%),10例(24%),9例(21%),9例(21%),7例(17%)犦,糖尿病5年组犤8例(36%),5例(23%),5例(23%),5例(23%),4例(18%)犦比较,差异有显著性意义(χ2=7.53～13.99,P<0.05～0.01)。结论:糖尿病合并冠心病患者冠状动脉受累程度随糖尿病患病年限增加而加重,是冠心病预后不良的独立危险因素。AIM:To investigate the characteristics of coronary arteriography in patients with type 2 diabetes mellitus(DM) and coronary heart disease(CHD). METHODS:Totally 122 patients receiving coronary arteriography in the Heart Center of Hebei Engineering College from June 2002 to February 2004 were enrolled in the study.Among the 122 patients,only 92 patients met the criteria, including 42 of non-DM(non-DM group),22 of 5-year type 2 DM(5-year DM group) and 28 of over 5-year type 2 DM(over 5-year DM group). Clinical data and characteristics of coronary arteriography were analyzed and compared among the three groups. RESULTS: There were no significant differences in the number of lesion vessels, degree of lesion and morphologic change between the over 5-year group and control group(P >0.05).There were 4 cases of single lesion(14%),12 of local lesion(43%),2 of three-vessel lesion(7%),9 of diffuse lesion(32%)and 8 of occluded lesion(29%)in the over 5-year group,correspondingly,14(33%),10(24%),9(21%),9(21%),7(17%)in the non-DM group,and 8(36%),5(23%),5(23%),5(23%),and 4(18%)in the 5-year group respectively.Significant difference was found among the three groups(χ2=7.53 to 13.99,P< 0.05 to 0.01). CONCLUSION:The degree of involved coronary artery, as an independent risk factor for bad prognosis of CHD,is more serious as the disease course increases in the patients with DM and CHD

关 键 词：糖尿病 非胰岛素依赖型/并发症 发病年龄 冠状动脉疾病/ 病因学:冠状动脉疾病/诊断 冠状血管造影术 

分 类 号：R587.1[医药卫生—内分泌]