东莨菪碱对豚鼠庆大霉素中毒性耳聋的预防作用  

PREVENTIVE EFFECT OF SCOPOLAMINA ON GENTAMYCIN INDUCED DEAFNESS IN GUINEA PIGS

作　　者：康颂建[1] 王文芳[1] 盖金芳 赵晓光[1] 董法和[2] 曾兆麟[3] 

机构地区：[1]泰山医学院生理学教研室 [2]泰山医学院设备科 [3]上海中医学院实验研究室

出　　处：《泰山医学院学报》1993年第1期11-14,共4页Journal of Taishan Medical College

基　　金：上海市卫生局基金

摘　　要：本研究以耳廓反射、耳蜗生物电和耳蜗铺片为指标,观察东莨菪碱对豚鼠庆大霉素中毒性耳聋的预防作用。实验结果表明东茛菪碱在听力下降程度及发病时间等方面均能减轻庆大霉素的耳毒性作用。The experiments have been performed using Preyer's reflex, cochlear potential, and surface preparation of the cochlear as indexes of the auditory function. The results indicate that the scopolamina reduces ototxicity produced by gentamycin on the degree of hearing loss and the time of hearing loss to occur.

关 键 词：庆大霉素 东莨菪碱 中毒性 耳聋 

分 类 号：R764.43[医药卫生—耳鼻咽喉科]