下颌骨截除后骨膜成骨的实验研究  

THE OSTEOGENIC CAPACITY OF PERIOSTEUM AFTER MANDIBULECTORY——AN EXPERIMENTAL STUDY

作　　者：王卫之[1] 孙涌泉[2] 张子桂[2] 张金池[3] 

机构地区：[1]泰山医学院口腔学教研室 [2]山东医科大学附属医院口腔科 [3]泰山医学院病理解剖学教研室

出　　处：《泰山医学院学报》1993年第4期280-284,共5页Journal of Taishan Medical College

摘　　要：选用24只家兔,于右侧下颌骨嚼肌前缘与颏孔之间造成10mm×5mm大小的骨缺损,保留骨膜进行下颌骨骨膜成骨能力的研究。左侧以同样方式去骨但不保留骨膜作对照。动物最长饲养8周,分别用肉眼、X线、组织学和扫描电镜观察。所有实验侧骨缺损完全骨化,对照侧骨缺损未修复。本实验得出如下结论:①下颌骨同膜成骨是一种普遍现象;②成骨以膜内骨生成方式完成,③术后7天即有类骨质产生;④骨膜成骨伴大量血管增生;⑤骨膜成骨细胞生发层以灶性成骨开始。In this experiment 24 rabbits were studied. The mandibular defects of 10mm×5mm, were created in both sides between tugomaxillary mulcle and mental foramen. The periosteukm was kept in the right side but was cut off in the left. The rabbits were feed- ed for 8 weeks after surgery. The osteogenic process was observed by gross: X-ray, histopathologic methods. It is found that the osteogenic precess was not oisible in the left side. Our findings suggest that: (1) mandibular periosteal osteogensis is a general law; (2) osteogenesis fulfils in the intramembranous osiffication; (3) osteogenesis begins as early as 7 days after surgery; (4) a lot of the blood vesseles form in the periosteal osteogenic prosses; (5) the bone formation starts in small loci of active osteoblasts.

关 键 词：骨膜 下颌骨 骨再生 成骨细胞 

分 类 号：R336[医药卫生—人体生理学]