冬虫夏草对肾性高血压大鼠心血管功能的影响  

Effect of Codyceps Sinensis on Cardiac and Vascular Function in Renal Hypertensive Rats

作　　者：吴秀香[1] 王国秋[2] 马克玲[2] 安鼎伟[3] 李淑云[2] 

机构地区：[1]锦州医学院病理生理教研室 [2]锦州医学院机能中心实验室 [3]锦州医学院附属第一医院

出　　处：《中西医结合心脑血管病杂志》2005年第2期137-138,共2页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

摘　　要：目的　观察青海产冬虫夏草对肾性高血压大鼠血压、心肌肥大、心血管功能的影响。方法　将体重 160 g～ 180 g健康雄性Wistar大鼠随机分为 3组 :对照组、高血压组及治疗组。于术后第 10天 ,大鼠灌胃冬虫夏草煎剂2mL ,每天 2次连续 2 0d ,观察冬虫夏草对大鼠血压、心肌肥大、心血管功能的影响。结果　冬虫夏草明显降低肾性高血压大鼠血压 ,改善高血压大鼠的心肌肥大及血管重构。结论　冬虫夏草对肾性高血压有治疗作用。Objective To observe the effect of codyceps sinensis on blood pressure,hypertensive cardiac hypertrophy and vascular remodeling.Methods Wistar rats were treated with codyceps sinensis twice a day for 4 weeks.The effect of codyceps sinensis on blood pressure,hypertensive cardiac hypertrophy and vascular remodling were investigated.Results The RH rats could be prevented significantly by treatment with codycedp sinensis since their cardiac hypertrophy and vascular remodeling were reversed.Conclusion codycops sinensis has a curable role on renal hyperteniverats.

关 键 词：冬虫夏草 肾性高血压 血压 心血管功能 

分 类 号：R285[医药卫生—中药学]