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作 者:何俐[1] 周沐科[1] 周东[1] 李宁[2] 吴滨[2]
机构地区:[1]四川大学华西医院神经内科,成都610041 [2]四川大学华西医院针灸科
出 处:《中国循证医学杂志》2005年第2期106-109,129,共5页Chinese Journal of Evidence-based Medicine
基 金:美国中华医学基金资助项目 (编号 98680 )。~~
摘 要:目的 系统评价针灸促进Bell s面瘫康复和减少其远期发病率的效果。方法 计算机检索MED LINE、EMBASE、LILAS、中国生物医学文献数据库和Cochrane肌肉疾病组注册组资料库 ,检索时间截止至 2 0 0 2年 12月 ;同时检索其它相关灰色文献 ,获取所有涉及针灸治疗Bell s面瘫的随机和半随机对照试验。而后选择符合纳入标准的临床试验 ,评价其方法学质量 ,并从中提取患者基本情况、干预措施、终点指标和结果等相关资料进行系统评价。结果 共有 3个小规模的临床随机对照试验 ,合计 2 88例患者符合纳入标准 ,但因其在试验设计、报道上存在明显缺陷 ,以及试验之间存在较大差异 ,不符合Meta分析条件 ,因而只进行了定性分析。结果显示 ,针灸治疗Bell s面瘫有一定疗效 (P均 <0.0 1)。结论 针灸治疗Bell s面瘫有效 ,但入选的 3个随机对照试验规模小 ,质量不高 ,降低了这一结论的可靠性。开展高质量、内在真实性好的相关随机对照试验非常必要。Objective To examine the efficacy of acupuncture in hastening recovery and reducing long term morbidity from Bells palsy. Methods We searched the Cochrane Neuromuscular Disease Group Register Group (Till Feb. 2002), MEDLINE (Jan. 1966 to Dec. 2002); EMBASE (Jan. 1980 to Dec. 2002), LILACS (Jan. 1982 to Dec. 2002) and Chinese Biomedical Retrieval System (Jan. 1978 to Dec. 2002). We also searched grey literature. We identified all randomised or quasi randomised controlled trials involving acupuncture in the treatment of Bells palsy, selected the trials ment the inclusion criteria, assessed the methodological quality, extracted data on trials patients, interventions, outcome measurements and results and undertook analysis. Results Three small randomised controlled trials were included but due to some flaws in study designs or reporting and clinical differences between trials, data from trials were not combined in a meta analysis,and a descriptive analysis was performed.The result indicated a positive effect of acupuncture (all P<0 01). Conclusions Three small studies in this review suggested a beneficial effect but the poor quality of the trials precludes us from drawing firm conclusions. There is a need for high quality randomized controlled trials (RCTs) using a study design which assures high internal validity.
分 类 号:R246[医药卫生—针灸推拿学]
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