载银ZrO_2无机抗菌剂的制备及性能研究  

Study on Preparation and Antibiotic Property of Ag-doped ZrO_2

作　　者：柳清菊[1] 朱忠其[1] 张瑾[1] 张海滨[1] 吴兴惠[1] 

机构地区：[1]云南大学材料科学与工程系,昆明650091

出　　处：《材料导报》2005年第1期104-105,111,共3页Materials Reports

基　　金：国家"863"计划项目(2002AA327090);云南省省长基金(2001)资助课题

摘　　要：以 ZrO_2为载体、银离子为抗菌成分制备无机抗菌材料,并对所制备的抗菌材料的抗菌性能及安全性能进行了分析检测,结果表明:在银盐的掺入量为1%～3%,烧结温度为600～1000℃时,所制备的样品对大肠杆菌及金黄葡萄球菌的 MIC 值均小于75×10^(-6);对大、小白鼠的急性经口毒性的 LD_(50)>10000mg/kg,急性经皮肤毒性的LD_(50)>3000mg/kg。The preparation technology and properties of Ag-type inorganic antibiotic material carried by ZrO_2 were studied.The results indicate that the better quantity of silver salt in the antibiotic material carried by ZrO_2 is 1%～3% and the better sintering temperature range is 600～1000℃.The materials prepared according to the above conditions are of good antibiotic and safety property,the MIC value is less than or equal to 75×10^(-6),the acute toxicity taken by stomata is LD_(50)>10000mg/kg and the acute toxicity on skin is LD_(50)>3000mg/kg(for little and big white rats).

关 键 词：制备 无机抗菌剂 ZRO2 银盐 载银 性能研究 抗菌性能 LD50 皮肤毒性 经皮 

分 类 号：TB383[一般工业技术—材料科学与工程] TQ174[化学工程—陶瓷工业]