不同炮制方法对化橘红中柚皮苷含量的影响  

Influence of Different Processing Technique on the Content of Naringin in Exocarpium Citri Grandis

作　　者：黄兰珍[1] 梁照恒 林励[1] 高道侠 欧剑锋[1] 

机构地区：[1]广州中医药大学中药学院,广州510405 [2]杭州华威药业有限公司,杭州311402 [3]江西省樟树市药品检验所,江西樟树331200

出　　处：《中药新药与临床药理》2005年第1期59-61,共3页Traditional Chinese Drug Research and Clinical Pharmacology

基　　金：国家科技攻关项目:"常用中药材化橘红规范化种植的研究"分课题(编号2001BA701AG1-8);广东省科技厅工业攻关重点项目:化橘红的加工生产工艺及其成套装置的研究(编号2003A1040309)。

摘　　要：目的以柚皮苷含量为指标,考察不同炮制方法对化橘红质量的影响。方法采用HPLC法测定柚皮苷含量,色谱柱:Kromasil ODS柱(250mm×4.6mm),流动相:甲醇-水-乙酸(35∶61∶4),流速∶1.0mL/min,检测波长:283nm,柱温:25℃。结果采用不同的炮制方法,化橘红柚皮苷含量有显著差异,以静电干燥明显高于烘干干燥、自然干燥和真空干燥。结论以静电干燥所得化橘红柚皮苷含量高,是炮制化橘红的较好方法。Objective To assess the influence of different processing technique on the quality of Exocarpium citri grandis.Methods The RP-HPLC method was adopted to determine the naringin content in Exocarpium citri grandis.The chromatographic conditions were: Kromasil ODS column(250 mm×4.6 mm),mobile phase being methanol-water-acetic acid(35∶61∶4),flow rate 1.0 mL/min,detection wavelength at 283nm and column temperature at 25 ℃.Results There were obvious differences in the naringin content of Exocarpium citri grandis which was processed by different methods: the naringin content processed by electro static drying method was much higher than that by bake drying method, natural drying method and vacuum drying method.Conclusion The electro static drying method is the best way for drying Exocarpium citri grandis.

关 键 词：化橘红 炮制 柚皮苷 含量测定 

分 类 号：R284.1[医药卫生—中药学]