不同透析膜对胰岛素、β_2-微球蛋白清除的临床观察及意义  

Clinical Study on Different Dialysis Membranes in Clearing Insulin and β_2-microglobulin

作　　者：孙蔚明[1] 张复兵[1] 陈敏[1] 朱旭[1] 孙秀荣[1] 张玉清[1] 

机构地区：[1]北京铁路总医院肾内科,北京100038

出　　处：《生物医学工程与临床》2000年第1期39-42,共4页Biomedical Engineering and Clinical Medicine

摘　　要：目的：了解不同透析膜对胰岛素、猓玻⑶虻鞍椎那宄芰Γ傅佳和肝鲋醒≡窀鲜实? 透析器，提高透析效果。方法：对１１例接受血液透析患者，第一个月应用血仿膜透析器，第二个月 应用聚以膜透析器，观察两种膜对胰岛素（Ｉｎｓ）、猓玻⑶虻鞍祝ㄢ２－ＭＧ）的清除能力。结果：血仿 膜对猓玻停乔宄芰τ庞诰垌磕ぃ砸鹊核氐那宄垌磕び庞谘履ぁ＝崧郏憾杂诔て诮邮苎a 液透析患者，交替使用血仿膜透析器和聚砜膜透析器，比单一使用血仿膜透析器或聚砜膜透析器 可收到更好的透析效果。Objective: The clearence ability of different dialysis membranes was studied in order to choose the appropriate membrane for dialyzer and improve the effect of dialysis. Methods: The study included 11 patients. All of the patients were dialyzed by hemophan dialyzer during the first month and polysulfone dialyzer during the second month. The ability for clearing insulin andResults: The capacity for clearing was better than that with polysulfone dialyzer. On the other hand, the clearence ability for insulin with hemophan dialyzer was poorer than polysulfone dialyzer. Conclusion: It is better to use hemophan dialyzer and polysulfone alternately in the patients treated by long-term dialysis.

关 键 词：透析器 胰岛素 Β2-微球蛋白 透析膜 Β2-MG 透析效果 血液透析患者 结论 指导 意义 

分 类 号：R459.5[医药卫生—治疗学] R587[医药卫生—临床医学]