美托洛尔对急性心肌梗死QT离散度及远期预后的影响  

Effect of metoprolol on QT dispersion and remote prognosis of AMI

作　　者：覃湘林[1] 陈丹[1] 王宏 

机构地区：[1]第四军医大学吉林军医学院附属医院心内科，吉林吉林132013 [2]吉林火电职工医院，吉林吉林132000

出　　处：《第四军医大学吉林军医学院学报（86813X）》2002年第4期197-198,共2页Journal of Jilin Military Medical College Fourth Military Medical University

摘　　要：目的探讨选择性β1-受体阻滞剂美托洛尔对急性心肌梗(AMI)患者的QT离散度(QTd)及心脏事件发生的影响。方法将68例AMI住院患者随机分为治疗组(33例)与对照组(35例)，治疗组在基础治疗的同时加用美托洛尔，对照组仅进行基本治疗；测定两组治疗前后QTd的变化和观察远期心脏事件发生率。结果治疗组QTd显著降低，与对照组比较差异显著(P＜0．05)；心脏事件发生率明显低于对照组(P＜0．05)。结论美托洛尔对AMI患者的QTd有改善作用，降低AMI患者的远期猝死及心衰发生率。Objective To explore the effect of metoprolol-a selective β 1- receptor inhibitor on QT dispersion of AMI and incidence of heart attack.Methods 68 inpatient cases with AMI were randomly divided into the treatment group(33 cases)and the control group(35 cases).The cases in the control group received only basic treatment while those in the treatment group were treated with metoprolol besides basic treatment and then the change of QTd and incidence of heart attack before and after treatment were determined...

关 键 词：美托洛尔 对照组 AMI 治疗组 患者 QT离散度 发生率 结论 目的 差异 

分 类 号：R541[医药卫生—心血管疾病] R542.22[医药卫生—内科学]