用肺功能指标推测慢性阻塞性肺病肺动脉平均压的探讨  

Pulmonary Artery Pressure Estimated by Pulmonary Function Testing in Patients with COPD

作　　者：陈光瑾[1] 杜文彬[1] 朱宝玉[1] 果春先[1] 王志强[1] 王化山[1] 

机构地区：[1]天津医学院附属医院,300052

出　　处：《天津医药》1993年第10期582-584,共3页Tianjin Medical Journal

摘　　要：对55例慢性阻塞性肺病进行右心导管测肺动脉压,同时测肺功能17项指标。肺动脉高压组与正常组经相关分析肺功能指标V_(75)%、V_(50)%、PEF%差异显著,VC%、V_(25)%、AEX%、Raw 差异非常显著。两组差异主要表现在反映小气道功能的指标。经微机多元逐步回归处理,推导出预测肺动脉平均压公式 s=5.58,r=0.63,经组内回代预测值与实测值比较 P>0.05,预测群体肺动脉压敏感性为73.1%、特异性71.4%、诊断正确率为72.2%,个体预测值与实测值差≤0.66kPa 者占68.5%,表明肺功能指标预测肺动脉平均压有一定应用价值。Department of Respiratory Medicine,Tianjin Medioal College HospitalPulmonary function tests and right heart catheterization were performed in 55patients with chronic obstructive pulmonary disease.Significant differences betweenthe normal control group and the pulmonary hypertension group were apparent inindexes (?)_(75%),(?)_(50%) and PEF%,and the differences were extremely apparent in VC%,(?)_(25%),and AEX%.The differences between the two groups were more obvious in in-dexes indicating small airway function.Regressive equations were established and theresults were used to predict mPAP quantitatively.The sensitivity,specificity anddiagnostic accuracy were 73.1%,71.4% and 72.2% respectively.We considered thatthe indexes of pulmonary function were useful for noninvasive estimation of pulmo-nary hypertersion in patients with CCPD.

关 键 词：肺功能 肺疾病 肺动脉压力 阻塞性 

分 类 号：R563[医药卫生—呼吸系统]