EFFECTS OF HERBAL CAKE-SEPARATED MOXIBUSTION ON BLOOD LIPIDS, PLASMA THROMOXANE B2 AND 6-KETO-PROSTAGLANDIN F_(1α) CONTENTS IN THE RABBIT WITH HYPERLIPEMIA  

作　　者：沈菁 常小荣 严洁 曹湘萍 岳增辉 

机构地区：[1]Hunan College of TCM, Changsha 410007, China

出　　处：《World Journal of Acupuncture-Moxibustion》2004年第4期41-46,共6页世界针灸杂志（英文版）

摘　　要：Objective: To observe effects of herbal cake-separated moxibustion on blood lipids, including total cholesterol (TCh), triglyceride (TG), high density lipoprotein-Ch (HDL-Ch), low density lipoprotein-Ch (LDL-Ch), apolipoprotein A (Apo A), apolipoprotein B (Apo B), and plasma thromboxane B2 (TXB2) and 6-keto-prostaglandin F 1α (6-keto-PGF 1α) contents and analyse its mechanism. Methods: The hyperlipemia rabbit model was established by breeding of high fat forage and injection of bovine serum albumin. They were treated respectively by direct moxibustion and herbal cake-separated moxibustion at Juque (巨阙 CV 14), Tianshu (天枢 ST 25), Fenglong (丰隆 ST 40), etc., once daily, continuously for 40 days. Blood TCh and TG contents were detected with enzymatic method, LDL-Ch and HDL-Ch with colorimetric method, Apo A and Apo B with electrophoretic method, and TXB2 and 6-keto-PGF 1α with radioimmunoassay. Results: Both the herbal cake-separated moxibustion and direct moxibustion could effectively decrease TCh, TG, LDL-Ch, Apo B and TXB2 contents and TXB2/6-keto-PGF 1α, and increase HDL-CH and 6-keto-PGF 1α contents in the rabbit of hyperlipemia. Conclusion: 6-keto-PGF 1α and TXB2 are possibly involved in the mechanism of herbal cake-separated moxibustion decreasing blood lipids.Objective: To observe effects of herbal cake-separated moxibustion on blood lipids, including total cholesterol (TCh), triglyceride (TG), high density lipoprotein-Ch (HDL-Ch), low density lipoprotein-Ch (LDL-Ch), apolipoprotein A (Apo A), apolipoprotein B (Apo B), and plasma thromboxane B2 (TXB2) and 6-keto-prostaglandin F 1α (6-keto-PGF 1α) contents and analyse its mechanism. Methods: The hyperlipemia rabbit model was established by breeding of high fat forage and injection of bovine serum albumin. They were treated respectively by direct moxibustion and herbal cake-separated moxibustion at Juque (巨阙 CV 14), Tianshu (天枢 ST 25), Fenglong (丰隆 ST 40), etc., once daily, continuously for 40 days. Blood TCh and TG contents were detected with enzymatic method, LDL-Ch and HDL-Ch with colorimetric method, Apo A and Apo B with electrophoretic method, and TXB2 and 6-keto-PGF 1α with radioimmunoassay. Results: Both the herbal cake-separated moxibustion and direct moxibustion could effectively decrease TCh, TG, LDL-Ch, Apo B and TXB2 contents and TXB2/6-keto-PGF 1α, and increase HDL-CH and 6-keto-PGF 1α contents in the rabbit of hyperlipemia. Conclusion: 6-keto-PGF 1α and TXB2 are possibly involved in the mechanism of herbal cake-separated moxibustion decreasing blood lipids.

关 键 词：Herbal cake-separated moxibustion  Hyperlipemia  TCh  TG  HDL-Ch  LDL-Ch  Apo  TXB2  6-keto-PGF    1α 

分 类 号：R245[医药卫生—针灸推拿学]