中国内蒙古鄂伦春、鄂温克、达斡尔族人五种酶型和二种血清型遗传多样性分析  

A Study of the Genetics Polymorphisms of Five Red Cell Isoenzymes and Two Serum Groups in the Oroqen,Ewenki and Dawuor Nationalities in the Chinese of Inner Mongolia

作　　者：刘牧[1] 沈淑萍[1] 马栓柱[1] 陈彩[1] 丁鑫[1] 赵英芳[1] 杨宏东[1] 童欢[2] 郭中辉[2] 王万胜[2] 刘建军[2] 堂吉斯 苏和 布仁 宝军 白立华 石刚 

机构地区：[1]内蒙古科技大学(原包头医学院)病理解剖教研室 [2]包头市公安局 [3]呼盟鄂温克自治旗医院 [4]鄂伦春族医院 [5]湖北省黄梅县医院

出　　处：《人类学学报》2005年第1期70-76,共7页Acta Anthropologica Sinica

基　　金：内蒙古高校科研基金资助(A95030);内蒙古"111工程"培养基金部分资助

摘　　要：应用G6PD ACP ADA AK1和GC Tf同步电泳的方法及GPT凝胶电泳的方法,分别对内蒙古境内鄂温克、鄂伦春、达斡尔族人476份血痕红细胞酶型:GPT、6 PGD、ACP、ADA、AK1和血清型GC、Tf的遗传多样性进行检测。根据所测表型频率分布、计算出基因频率分布,识别能力和累积识别能力,就其多态性特征及其在法医学鉴定中的应用价值进行了分析讨论。同国内外不同资料进行了比较研究,阐明了三群体上述酶型和血清型遗传多样性分布的规律和特点。从血型遗传学角度探讨了鄂伦春、鄂温克、达斡尔族间的族源、血缘关系。被调查人群中未发现各酶型和血清型的变异型。Red cell isoenzymes GPT, 6-PGD, ACP, ADA, AK1 and the serum group GC-Tf are genetic polymorphisms that are inherited according to the Mendelian law of segregation. In this paper, the phenotype frequencies of the GPT, 6-PGD, ACP, ADA, AK1 and GC-Tf have been investigated by the method of typing GPT-ACP-6PGD-ADA-AK1 and Gc-Tf on the same mixed starch agarose gel electrophoresis among seven Chinese nationalities, Ewenki,Oroqen and Dawuor.The distribution of their type frequencies varied with ethnic group and the gene frequencies, DP and CDP were also calculated. The ranges of gene frequencies of Ewenki, Oroqen and Dawuor were: GPT^10.46875-0.47225, 6-PGD^A0.8563-0.8583, ACP^A0.2139-0.2208, ADA^10.9500-0.9596, AK^1(1) 0.9963-1.000, Gc^1 0.64375-0.65445, Tf^c 0.9669-0.96945. The DP were: GPT 0.6288-0.6303, 6-PGD 0.3999-0.4037, Acp 0.4916-0.5187, ADA 0.1487-0.1800, AK1 (0-0.0111), GC 0.5839-0.6029, Tf 0.1147-0.1236. No rare genes of other isoenzymes or serum groups were found.The differences in the distribution of 5 isoenzymes and 2 serum groups in the 3 ethnic groups were analyzed. It was found that there were many similarities in the genetic characters of the Oroqen, Ewenki and Dawuor herdsmen populations addressed in the past 'suoluner', showing the possible common blood ties of these 3 populations, which has been recorded in the historical data.

关 键 词：酶型 血清型 遗传多态性 基因频率 鄂温克族 鄂伦春族 达斡尔族 内蒙古 

分 类 号：Q987.2[生物学—遗传学]