2,6-二-O-丙基-β-CD键合硅胶固定相的合成与色谱性能考察  

Preparation and chromatographic characteristics of 2,6-di-O-propyl-β-cyclodextrin bonded silica stationary phase for high performance liquid chromatography

作　　者：刘立文[1] 罗爱芹[2] 戴荣继[2] 张金专[1] 方敏[1] 

机构地区：[1]中国人民武装警察部队学院,廊坊065000 [2]北京理工大学,北京100081

出　　处：《分析试验室》2004年第12期32-34,共3页Chinese Journal of Analysis Laboratory

摘　　要：合成2,6 二 O 丙基 β CD键合硅胶固定相(PCDS);利用傅里叶红外光谱、X射线光电子能谱、莫氏(Molisch)试验颜色反应进行了表征;以邻苯二甲酸二甲酯、甲苯和菲为测试溶质,评价该键合固定相的色谱性能;并考察了该固定相对一些位置异构体和手性药物的色谱分离效果;讨论了可能的分离机理。A 2,6-di-O-propyl-β-cyclodextrin bonded stationary phase(PCDS) was prepared. The resulted bonded silica was characterized by three methods. The chromatographic performances of PCDS by separating isomers were investigated, and its retention mechanism was also discussed.

关 键 词：高效液相色谱 2 6-二-0-丙基-β-CD 键合硅胶 固定相 对映体 

分 类 号：O657.72[理学—分析化学]