原发性骨质疏松症放射性核素骨显像定量研究  

Quantitative bone uptake measurement by bone scintigraphy in patients with primary osteoporosis

作　　者：郭兴[1] 李林[1] 

机构地区：[1]四川大学华西医院核医学科,成都610041

出　　处：《国外医学（放射医学核医学分册）》2004年第6期259-262,共4页Foreign Medical Sciences(Section of Radiation Medicine and Nuclear Medicine)

摘　　要：原发性骨质疏松症是以骨量减少、骨的微观结构退化为特征,致使骨的脆性增加以及易于发生骨折的一种全身性骨骼疾病。其骨的转换表现出从高转换到低转换的特点。许多定量骨扫描测量方法被用于研究骨质疏松,放射性核素定量骨扫描是一种评价骨质疏松相当精确和有用的方法。Osteoporosis has many causes and different clinical presentations, all characterized by a loss of bone tissue to a level below that required for mechanical support of every day activities, resulting in nontraumatic fractures. Bone turnover may range from accelerated to severely reduced. Quantification of skeletal uptake of radionuclide have been evaluated to assess bone turnover. Different technical approaches have been described over years. Radionuclide quantitative bone scaning may be reasonably accurate and useful for the assessment of osteoporosis.

关 键 词：骨质疏松 放射性核素成像 定量分析 ^99Tc^m-亚甲基二膦酸盐 

分 类 号：R817.4[医药卫生—影像医学与核医学]