Synthesis and Crystal Structure of Spiro[1-bromo-4-methoxy-5-oxa-6-oxo-bicyclo[3.1.0]hexane-2,2′-(3′-cyclohexanoxy-4′-methoxybutyrolactone]  

作　　者：YUZhao-Lian LISen-Lan GUOJin-Bo CHENQing-Hua 

机构地区：[1]DepartmentofChemistry,LuoyangNormalCollege,Henan,Luoyang470022,China

出　　处：《Chinese Journal of Structural Chemistry》2005年第1期94-98,共5页结构化学（英文）

基　　金：Supported by the National Natural Science Foundation of China (No. 29672004)

摘　　要：The crystal of the title compound 6 has been prepared and determined by X-ray diffraction analysis. It belongs to the orthorhombic system, space group P212121 with a = 10.195(2), b = 11.955(2), c = 14.335(3) ?, C16H21BrO7, Mr = 405.24, V = 1747.0(6) ?3, Z = 4, Dc = 1.541 g/cm3, μ = 2.387 mm-1, F(000) = 832, R = 0.0266 and wR = 0.0348 for 2110 observed reflections with I > 2σ(I). The crystal exhibits a characteristic spiral structure consisting of one cyclopropane and two butyrolactones with envelope configuration. The intermolecular hydrogen bond between C(16)– H(16)…O(1) and C(3)–H(3)…O(2) has been observed in the crystal lattice.The crystal of the title compound 6 has been prepared and determined by X-ray diffraction analysis. It belongs to the orthorhombic system, space group P212121 with a = 10.195(2), b = 11.955(2), c = 14.335(3) ?, C16H21BrO7, Mr = 405.24, V = 1747.0(6) ?3, Z = 4, Dc = 1.541 g/cm3, μ = 2.387 mm-1, F(000) = 832, R = 0.0266 and wR = 0.0348 for 2110 observed reflections with I > 2σ(I). The crystal exhibits a characteristic spiral structure consisting of one cyclopropane and two butyrolactones with envelope configuration. The intermolecular hydrogen bond between C(16)– H(16)…O(1) and C(3)–H(3)…O(2) has been observed in the crystal lattice.

关 键 词：multi-functionlized spiro-cyclopropane bioactivity crystal structure synthesis 

分 类 号：O624.5[理学—有机化学]