鹿茸中神经节苷脂的成分研究  

Study on gangliosides of pilose antler

作　　者：高越[1] 尹一子[1] 李子健[1] 张大军[2] 

机构地区：[1]吉林大学第一医院药剂科,吉林长春130021 [2]吉林省中医中药研究院,吉林长春130021

出　　处：《吉林医学》2004年第12期37-38,共2页Jilin Medical Journal

摘　　要：目的:分离鉴定鹿茸中神经节苷脂的成分。方法:Folsh分配、DEAE-Cellulose柱层析分离、薄层色谱方法鉴定。结果:分离鉴定出3种组分(A、B、C),与对照品薄层图谱对照,鉴定了A为GM4,B为GM3,C为GD3,A、B、C的百分含量分别为24.4%、46.2%、29.4%。结论:首次从鹿茸中分离出GM4,GM3,GD33种神经节苷脂成分。Objective To study the chemical constituents of gangliosides(GLS) from the pilose antler. Method Folsh distribution, EDTA-Cellulose chromatography, TLC were used to isolate and identify compounds. Results Three components (A,B,C) were isolated from pilose antler and compared with GLS standards. A, B ,C were successively identified as GM4, GM3, GD3. Percentage contents of A,B,C were 24.6%, 6.2%, 29.4%. Conclusion Three components(GM4, GM3, GD3) were first separated from pilose antler.

关 键 词：鹿茸 神经节苷脂 TLC鉴定 

分 类 号：R284[医药卫生—中药学]