基质调控碳酸钙生物矿化过程及其体外模拟的研究进展  

Research progress on biomineralization process of calcium carbonate mediated by organic matrix and its simulation

作　　者：欧阳健明[1] 

机构地区：[1]暨南大学生物矿化与结石病防治研究所

出　　处：《功能材料》2005年第2期173-176,180,共5页Journal of Functional Materials

基　　金：国家自然科学基金重点资助项目(20031010);广东省自然科学重点基金资助项目(013202);广东省重点攻关项目资助项目(C31401);广东省"千百十工程"优秀人才培养基金资助项目(Q02060);南京大学配位化学国家重点实验室开放基金资助项目(1408)

摘　　要：　生物体内碳酸钙的矿化过程受有机基质的调控。本文综述了基质蛋白和各类模型基质调控下碳酸钙矿化的研究进展。有机基质提供碳酸钙成核和生长的模板,调控碳酸钙晶体的结晶学取向、晶型和形貌,使形成的碳酸钙晶体具有特定的理化性质。同时,碳酸钙也可影响有机基质的微观结构。The mineralization process of calcium carbonate (CaCO3) in vivo was mediated by organic matrix. The research progress on the biomineralization of CaCO3 in vitro mediated by organic matrix and synthetic organic compounds was reviewed in this paper. Organic matrix provides the template of nucleation and growth of CaCO3, and mediates the crystallographic orientation, polymorph and morphology of CaCO3. It gives these CaCO3 crystals special physical and chemical properties. On the other hand, CaCO3 crystals also influence the micro-structure of organic matrix.

关 键 词：碳酸钙 生物矿化 基质调控 

分 类 号：O61[理学—无机化学]