狂犬病疫苗免疫效果观察的研究(一)  

Study on Immunization Effects of the Rabies Vaccine

作　　者：李根明[1] 王辉[1] 邹勇[1] 袁晓培[1] 杨瑛[1] 严子林[2] 

机构地区：[1]卫生部兰州生物制品研究所,兰州730046 [2]中国药品生物制品检定所

出　　处：《微生物学免疫学进展》1993年第2期16-20,共5页Progress In Microbiology and Immunology

摘　　要：本试验通过改变现用疫苗的免疫程序及免疫方法,比较不同免疫程序的肌肉免疫和皮内减量免疫与常规免疫方法免疫后血清中和抗体水平,阳转率,免疫持久性等。试验结果表明,肌肉免疫法2-1-1及皮内减量法,即可减少疫苗用量,免疫效果亦优于常规法。The neutralizing antibody level of serum, seroconversion rate and immunization period were determined after immunizing by means of different administratrated methods,e. g. intramuscular ( IM ) injection, intracutaneous ( IC ) injection with reduced amount of vaccine in compared with those of by routine way. The results shown that the administratedMnount of IM and IC w y not only can be decreased but also their immune effects are superior to that of routine method

关 键 词：狂犬病 疫苗 免效学 

分 类 号：R392－33[医药卫生—免疫学]