糖耐量受损患者血清可溶性E选择素和血管细胞黏附分子1的水平  

Serum levels of soluble E-selectin and vascular cell adhesion molecule-1 in patients with impaired glucose tolerance

作　　者：李鹏飞 张爱珍[2] 

机构地区：[1]镇海龙赛医院内分泌科,宁波315200 [2]浙江大学医学院附属第二医院内分泌科

出　　处：《中华内分泌代谢杂志》2005年第1期29-30,共2页Chinese Journal of Endocrinology and Metabolism

摘　　要：　用ELISA法测定 62例糖耐量受损(IGT)患者、24名正常糖耐量 (NGT)者和 23例 2型糖尿病患者可溶性E选择素和可溶性血管细胞黏附分子 1(sVCAM 1)的血清水平,发现IGT患者sVCAM 1浓度明显高于NGT者,提示IGT患者已发生不同程度的血管内皮细胞功能障碍。The serum levels of soluble E selectin (sE selectin) and soluble vascular cell adhesion molecule 1 (sVCAM 1) were determined by ELISA in impaired glucose tolerance (IGT) group (62 cases), normal glucose tolerance (NGT) group (24 subjects), and diabetes mellitus group (23 cases). Serum sVCAM 1 level in the IGT group was significantly higher than that in the NGT group (P<0.01). It suggests that an early endothelial dysfunction to various extents is present in the patients with IGT.

关 键 词：患者 可溶性E选择素 糖耐量受损 血管细胞 黏附分子 IGT SVCAM-1 水平 发现 

分 类 号：R587[医药卫生—内分泌] R714.246[医药卫生—内科学]