性病门诊患者单纯疱疹病毒血清型特异性抗体的检测  

Determination of Serum HSV type Particularity Antibody in Outpatients with Sexually Transmitted Diseases

作　　者：黄进波 方小娴 杨启平 林晓燕 

机构地区：[1]广东省汕头市皮肤医院,广东汕头515041

出　　处：《中国皮肤性病学杂志》2005年第2期103-104,共2页The Chinese Journal of Dermatovenereology

摘　　要：目的了解本地区性病门诊患者单纯疱疹病毒感染的血清学特征。方法用酶联免疫吸附试验法对864例性病患者及100例健康对照人群进行血清HSV1及HSV2抗体检测。结果性病患者血清HSV1IgM,HSV1IgG,HSV2IgM,HSV2IgG抗体阳性率分别为13.8%,90.3%,15.4%,42.4%,明显高于健康对照者的5.0%,82.0%,0,4.0%。女性患者HSV1型和2型IgM抗体阳性率分别为17.3%和23.0%,明显高于男性患者的11.0%和9.0%;男女患者HSV1型和2型IgG抗体阳性率均无统计学差异。结论性病门诊患者HSV感染严重,尤其是HSV2感染。对血清HSV2抗体阳性者采取行为干预及预防性治疗,对降低HSV传播的危险性及复发频率具有十分重要的意义。Objective To understand the serum characteristic of herpes simplex virus infection in outpatients with sexually transmitted diseases.Methods Serum HSV antibody was determined by ELISA in 864 outpatients with sexually transmitted diseases and 100 control people.Results The seropositive rates HSV1-IgM,HSV1-IgG,HSV2-IgM,HSV2-IgG were 13.8%,90.3%,15.4%,42.4% respectively in outpatients with sexually transmitted diseases, obvious higher than the health control people of 5.0%,82.0%,0,4.0%. HSV1-IgM and HSV2-IgM seropositive rates were 17.3%,23.0% respectively in female patients, obvious higher than the male patients of 11.0%,9.0%. HSV1-IgG and HSV2-IgG seropositive rates have no statistics difference in the men and women.Conclusion HSV infection in outpatients with sexually transmitted diseases was serious, especially to HSV2. Using behavior interference and previously treatment to the HSV-2 antibodies seropositive patients was importance.

关 键 词：单纯疱疹病毒 型特异性抗体 

分 类 号：R711.72[医药卫生—妇产科学]