银杏叶总黄酮的抗自由基作用  

THE RESEARCH OF ANTI-FREE RADICAL ACTION OF GINKGOBILOBAL TOTL FLAVONE

作　　者：耿秀芳[1] 徐瑗民 刘同美[2] 郭淑睿 钟桂美 李桂芝[1] 

机构地区：[1]潍坊医学院生化教研室 [2]潍坊医学院病生教研室 [3]中医学教研室 [4]潍坊医学院保健科

出　　处：《潍坊医学院学报》1993年第1期10-12,共3页Acta Academiae Medicinae Weifang

摘　　要：用80%乙醇提取银杏叶总黄酮(1.9mg/ml 提取液)按每日5ml/kg 体重给大白鼠腹腔注射,用水提取银杏叶总黄酮(0.95mg/ml)给大白鼠口服,每日10ml/kg 体重。实验40d 后,心脏取血,检测其抗自由基指标:过氧化脂质(LPO)含量和超氧化物歧化酶(SOD)活力变化以及血粘度。结果表明水提银杏叶黄酮有抗自由基作用,醇提银杏叶黄酮有提高 SOD 活力和降低血粘度作用。Ginkgobilobal flavone(1.9mg/ml the content)extracted with 80% alcohol was injected into abdominal cavity of the rats;The rats taken orally ginkgobilolal flavone (0.95mg/ml the content)extracted with water.Forty days after the test,the test of the blood taken from rats heart examined that the level of anti-free radical:lipid peroxides.superoxide dismutase and blood vis- cosity.The water-solubilized flavone had anti-free effect,alcohol extracted flavone had the effect of raising activity of SOD and decreasing blood viscosity.

关 键 词：银杏叶 过氧化脂质 自由基 

分 类 号：R284.1[医药卫生—中药学]