西洋参叶20s-原人参二醇组皂苷对小鼠心肌营养性血流量的影响  

Effect of Panax quinquefolium20s-protopanaxdiolsaponins on the Nutritional Blood Flow of Myocardium in Mice

作　　者：翟丽杰[1] 于小风[1] 曲绍春[1] 睢大员[1] 

机构地区：[1]吉林大学药学院药理教研室,长春130021

出　　处：《人参研究》2004年第4期2-4,共3页Ginseng Research

基　　金：吉林省科学技术厅新药基金项目 (吉科合字第 962 90 1 - 1 )

摘　　要：通过小鼠心肌86Rb摄取率实验 ,观察西洋参叶 2 0s -原人参二醇组皂苷 (PQDS)对小鼠心肌营养性血流量的影响。结果表明 ,PQDS 5 0、1 0 0mg/kg均可明显增加小鼠心肌86Rb摄取率 ,2 5mg/kg亦有增加小鼠心肌86Rb摄取率的趋势 ,提示PQDS能增加心肌营养性血流量。Effect of Panax quinquefolium 20s-protopanaxdiolsaponins (PQDS) on the nutritional blood flow of myocardium was observed with test of introjecion 86Rb in mice. The results showed that PQDS (50,100mg/kg) couldincrease significantly myocardial introjection rate of 86Rb and G-Rb (25mg/kg) had the tendency of increasing myocardial introjection rate of 86Rb. It is indicated that PQDS can increase the nutritional blood flow of myocardium in mice.

关 键 词：小鼠 心肌营养性血流量 人参二醇 皂苷 摄取率 西洋参 影响 增加 趋势 

分 类 号：R285[医药卫生—中药学]