人窦房结胶原纤维网架的构筑  

Architecture of collagen tissue fibers of human sinoatrial node

作　　者：樊宇兵[1] 张兴和[1] 王保芝[2] 王丽 张朝欣[1] 

机构地区：[1]解放军白求恩军医学院解剖学教研室,石家庄050081 [2]河北医科大学解剖学教研室 [3]河北医科大学电镜实验中心

出　　处：《解剖学杂志》2004年第6期668-670,共3页Chinese Journal of Anatomy

摘　　要：目的 :观察人窦房结胶原纤维网架的构筑及其与窦房结中央动脉的关系。方法 :用NaOH消蚀法扫描电镜观察成人窦房结。结果 :人窦房结中央动脉管壁的纤维网架分为内膜、中膜和外膜 3层 ;在窦房结中央动脉周围 ,形成厚约 5 0～ 80 μm的致密的动脉周围层 ;再向外是中央层 ,窦房结实质细胞就位于其胶原纤维隔围成的直径约 8～ 1 6μm的孔洞中 ;中央层与普通心肌胶原纤维网架间的界限明显。 结论 :人窦房结胶原纤维网架的构筑 ,有利于消除中央动脉博动的影响 。Objective:To investigate the architecture of collagen fibers of human sinoatrial node and its relationship to the central artery penetrated to the node. Methods:The human sinoatrial node in 11 adult hearts was studied by NaOH-maceration and SEM.Results:The collagen fibers of the central artery penetrated to the node may be divided into 3 layers: intima, media and adventitia. The dense periarterial layer (50-80 μm in diameter) was composed of the collagen fiber bundles (20 μm in diameter), which were assembled densely around the central artery. The central layer was around the periarterial layer. There were many collagen fiber bundles similar to the periarterial layer's group in the central layer. The collagen fiber septula originating from the collagen fiber bundles formed holes in the central layer. The parenchymal cells of sinoatrial node located in the holes and connected with each other. There were an obvious boundary between collagen fiber networks of the central layer and normal cardiac muscle cells. Conclusion:The collagen fiber network of human sinoatrial node is more advantageous to support, stabilize, protect and nourish the parenchymal cells of sinoatrial node, which may contribute to maintaining a specific suitable microenvironment for their activities.

关 键 词：窦房结 动脉 胶原纤维 内膜 NAOH消蚀法 心肌胶原 外膜 结实 纤维网 扫描电镜观察 

分 类 号：R322[医药卫生—人体解剖和组织胚胎学] R541[医药卫生—基础医学]