三种静脉注射方法对化疗患者的影响  

作　　者：范爱飞[1] 丁小容[1] 石兰萍[1] 郭辉[1] 匡剑英[1] 王素红[1] 

机构地区：[1]北京大学深圳医院血液科,广东深圳518036

出　　处：《现代临床护理》2005年第1期4-6,共3页Modern Clinical Nursing

摘　　要：目的通过比较三种静脉注射方法,为化学治疗(柔红霉素+阿糖胞苷)的肿瘤患者选择良好静脉通道,探讨避免或减少化疗药物产生局部毒性反应的方法。方法将143例急性白血病患者随机分为三组,常规组(经外周静脉直接输注化疗药物)46例,改良组(经外周静脉直接输注化疗药物前后采取系统的预防护理措施)48例,经外周静脉置入中心静脉导管(PICC)49例为PICC组。比较三组患者行化学治疗静脉给药过程中,组织渗漏性损伤及静脉炎等局部毒性反应的情况。结果三组组织渗漏性损伤及静脉炎发生率两两比较,有统计学意义(均P﹤0.05),改良组组织渗漏性损伤、化疗性静脉炎发生率明显低于常规组,而PICC组又明显低于改良组。结论接受化学治疗的患者应用PICC途径输注最为安全可靠,能有效控制组织渗漏性损伤及静脉炎等局部毒性反应的发生。Objective To set up a good venous path for patients with tumour to decrease local toxic reaction by comparison of three injection methods. Methods One hundred and forty three patients with leukaemia were randomly divided into three groups according to injection methods of DA chemotherapy: the general group (injection through peripheral vein), the improved group (system nursing measures were performed before and after injection through peripheral vein), and the parenterrally inserted central catheter (PICC) group. Local toxicity reactions including tissue leaky damage and venulitis were compared among these three groups. Results There were significant differences among these three groups in terms of tissue leaky damage and venulitis. Conclusion PICC is the first choice for patients who accepted DA chemotherapy because it can decrease the occurrence of tissue leaky damage and venulitis.

关 键 词：渗漏性损伤 经外周静脉 静脉炎 输注 PICC 毒性反应 化疗药物 患者 局部 化学治疗 

分 类 号：R472[医药卫生—护理学] R473.73[医药卫生—临床医学]