影响新生儿机械通气疗效的相关因素  

Factors in relation with the efficacy of mechanical ventilation in neonates

作　　者：谢利娟[1] 朱晓东[1] 朱建幸[1] 

机构地区：[1]上海第二医科大学新华医院儿内科,上海200092

出　　处：《上海第二医科大学学报》2004年第12期1059-1060,1063,共3页Acta Universitatis Medicinalis Secondae Shanghai

摘　　要：目的分析影响机械通气疗效的有关因素 ,提高治疗新生儿呼吸衰竭成功率。方法 1998～ 2 0 0 3年入住本院新生儿重症监护室进行机械通气治疗且资料完整的患儿 172例 ,对其疗效相关因素进行回顾性总结和分析。结果 172例患儿中 ,死亡 5 0例 ,其原发疾病主要为新生儿窒息 (2 0例 )和新生儿呼吸窘迫综合征 (16例 )。胎龄、出生体重与机械通气疗效显著相关 (P <0 .0 5 )。发病至上呼吸机时间 ,存活组显著早于死亡组 (P <0 .0 5 )。上呼吸机持续时间以 3～ 5d的抢救成功率最高。结论及早上呼吸机 ,结合患儿自身特点和病情变化合理选择通气模式 ,积极防止并发症 ,可进一步提高机械通气治疗的成功率。Objective To improve the outcome of the treatment for neonatal respiratory failure, a retrospective analysis of the factors in relation with the efficacy of mechanical ventilation in neonates was conducted. Methods One hundred and seventy-two newborn infants admitted to the NICU and on mechanical ventilation(MV) during 1998 to 2003 with complete data were enrolled in the study. The factors associated with their outcomes were analyzed. Results The clinical data showed that there were significant differences in gestation age and birth weight between the deceased and survived(P<0.05 ). It indicated that smaller the gestation age and lower the birth weight were higher the mortality was. There was also a statistically significant difference in the time from onset of respiratory failure to put-on MV between the deceased and survived (P<0.05). There was a high success rate for those treated with the machine for 3 to 5 days. Conclusion Early intervention with MV and adequate selection of the MV modes are required for the neonates with respiratory failure to prevent complication and to improve the outcomes.

关 键 词：机械通气治疗 疗效 呼吸机 相关因素 并发症 患儿 新生儿 结论 特点 目的 

分 类 号：R722.1[医药卫生—儿科]