广西地区泌尿生殖道支原体感染状况及体外药敏结果分析  

ANALYSIS OF MYCOPLASMA FROM GENITAL-URINARY TRACT SPECIMENTS OF GUANGXI ZHUANG AUTONOMOUS REGION

作　　者：农生洲[1] 覃桂芳[1] 覃迺辉[1] 唐萍[1] 王勇[1] 陈松峰[1] 

机构地区：[1]广西壮族自治区人民医院,南宁530021

出　　处：《广西医科大学学报》2004年第6期830-831,共2页Journal of Guangxi Medical University

基　　金：广西青年科学基金资助项目 ( No.桂科青 0 13 5 0 17)

摘　　要：目的 :了解广西地区泌尿生殖道感染状况及标本分离的支原体的耐药状况 ,以指导临床合理用药。方法 :采用支原体培养、计数、药敏一体化试剂盒 ,对泌尿生殖道感染患者标本分离的支原体进行检测。结果 :10 5 2 8例患者培养阳性 5 96 1例 ,阳性率为 5 6 .6 2 % ;男性培养阳性 10 5 8例 ,阳性率为 34.0 0 % ;女性培养阳性 4 90 3例 ,阳性率为 6 6 .11% ;解脲支原体 (U u)单项感染率为 6 4 .0 6 % ,U u和人型支原体 (Mh)混合感染率为 17.17% ,Mh单独感染率为 1.2 2 % ;药敏试验结果 :U u敏感率最高为克拉霉素 (85 .97% )和交沙霉素 (87.88% ) ,而 Mh敏感率最高为交沙霉素 (78.4 0 % )。结论 :广西地区泌尿生殖道感染女性高于男性 ,以 Uu单项感染为主 ,分离的支原体具有严重的耐药性。必须加强耐药监测 ,选择应用敏感有效的抗菌药物 。Objective:Investigation of Mycoplasma from genital-urinary tract speciments and susceptibility of Ureaplasma urealyticum(Uu) strains and Mycoplasma hominis (Mh)strains to antimicrobial agents.Methods:Combination of Uu and Mh culture and susceptibility testing were from Zhuhai Langfeng Biotech Co.Ltd.for isolation and susceptibility testing of Uu and Mh.Result:4 809 cases (45.68%) were Uu positive, 78 cases (1.22%) were Mh positive,1 096 cases (17.17%) were both Uu and Mh positive. Significant diference in Mycoplasma infection rate was observed between men and women patients(P<0.01). there were Josanmycin and Clarithromycin were more than 85.97% susceptible to Uu strains, and Josanmycin was more than 78.40% susceptible to Mh strains.Conclusion:Both the Uu and Mh isolated from genital-urinary tract speciments of Guangxi area have been resistant to most of common in use antibiotics. It is important for doctors to use susceptibility testing results to select efective drugs and reduce resistance.

关 键 词：泌尿生殖道 支原体 药物敏感试验 

分 类 号：R518.9[医药卫生—内科学] R691.3[医药卫生—临床医学]