正常前列腺MR弥散成像的初步应用  

The Preliminary Application of MR Diffusion-weighted Imaging in the Normal Prostate

作　　者：张继斌[1] 沈钧康[2] 李晓兵[1] 许建铭[1] 须同禄[1] 刘仁坚[1] 陆之安[2] 

机构地区：[1]苏州市第二人民医院放射科,江苏苏州215002 [2]苏州大学附属第二医院MRI室

出　　处：《实用放射学杂志》2004年第12期1118-1120,1126,共4页Journal of Practical Radiology

摘　　要：目的　探讨MR弥散成像 (DWI)在正常前列腺中的特点及应用价值。方法　随机选择无泌尿系统疾病的健康志愿者 3 0名 (年龄 2 0～ 40岁 ) ,采用SiemensSymphony 1.5T磁共振成像系统 ,在平面回波成像 (EPI)基础上进行MR弥散成像 ,并计算前列腺中央带和外周带的平均表观弥散系数。结果　MR弥散成像能较清晰地显示正常前列腺的中央带和外周带 ,其平均表观弥散系数分别为 :(1.883± 0 .3 7)× 10 -3 mm2 /s ,(2 .2 5 4± 0 .77)× 10 -3 mm2 /s ;大b值、大b值差所测得的ADC值更精确 ;3种成像方式 (DWI、T2 WI、T2 WI +FS)中对比噪声比 (CNR)无显著性差异 (Ρ >0 .0 5 )。结论　 1.5T磁共振成像系统可以进行正常前列腺的MR弥散成像 ,有望对前列腺疾病的机理研究和临床诊断提供新的帮助。Objective To explore the characteristics and useful value of MR diffusion-weighted imaging in the normal prostate.Methods MRI scanning(1.5T Siemens Symphony MR unit) was performed in thirty healthy volunteers who were not suffered from the prostatic diseases,age from twenty to forty years old,using echo planar imaging (EPI).Results Diffusion-weighted imaging can display the central gland and peripheral zone of the normal prostate, and the average apparent diffusion coefficients of them was:(1.883±0.37)×10 -3 mm 2/s,(2.254±0.77)×10 -3 mm 2/s respectively . It was more accurate when using large b value and large b value remainder. There were no statistical difference about contrast to noise among DWI,T 2WI and T 2WI+FS (P>0.05). Conclusion MR diffusion-weighted imaging of the normal prostate can be obtained with 1.5T MR scanner and are of help for studying the mechanism of the prostatic diseases as well as for making clinical diagnosis.

关 键 词：前列腺 磁共振成像 弥散 

分 类 号：R322.64[医药卫生—人体解剖和组织胚胎学] R445.2[医药卫生—基础医学]