复方甘草酸苷治疗抗肿瘤药导致肝损害的疗效观察  

Clinical Effects of SNMC^(TM) on Liver Injury Induced by Anti-Tumor Medicine

作　　者：郑滢[1] 宋方闻[2] 庄学龙[1] 吴悦义[1] 

机构地区：[1]广东汕头大学医学院附属肿瘤医院,汕头市515031 [2]广州医学院南大学院,广州市510320

出　　处：《中国药房》2005年第3期207-208,共2页China Pharmacy

摘　　要：目的 :观察复方甘草酸苷治疗抗肿瘤药导致肝损害的疗效。方法 :将60例应用抗肿瘤药导致肝功能损害的患者随机分成治疗组 (32例 )和对照组 (28例 ) ,治疗组在对照组用药基础上加用复方甘草酸苷。结果 :治疗组在丙氨酸氨基转移酶、天门冬氨酸氨基转移酶、总胆红素的改善程度上均明显优于对照组 (P<0.01)。结论 :复方甘草酸苷有很好的保肝降酶、抗炎、免疫调节作用 ,未见不良反应 ,用药安全 ,推荐用于治疗抗肿瘤药导致的肝损害。OBJECTIVE:To observe the clinical effects of Stronger Neo-Minophagen C(SNMC)in the treatment of liver function damage caused by anti-tumor medicine.METHODS:60cases of liver injury caused by anti-tumor medicine were randomly divided into the treatment group(32cases)and the control group(28cases).SNMC injection was given in the treatment group as a supplement to the primary therapy in the control group.RESULTS:The treatment group with SNMC showed significantly greater improvement than the control group in the liver functions(ALT,AST,T.BIL)(P<0.01).CONC_ LUSION:SNMC is effective for liver function damage caused by anti-tumor medicine for its protective,anti-inflammatory,and immunity-regulatory function.SNMC is also a secure medicine with less side effects and therefore is recommendable for treatment of liver injury caused by anti-tumor medicine.

关 键 词：复方甘草酸苷 抗肿瘤药 肝损害 疗效 

分 类 号：R975.5[医药卫生—药品]