正交试验优选冰片脂质体制备工艺的研究  

Study on the Preparation Craft Selecting Liposome of Borneolum Syntheticum With Orthogonal Design

作　　者：任卫琼[1] 陈维旗[1] 廖建萍[1] 

机构地区：[1]湖南中医学院第一附属医院,湖南长沙410007

出　　处：《湖南中医药导报》2005年第1期67-68,共2页Hunan Guiding Journal of Traditional Chinese Medicine and Pharmacology

摘　　要：目的 :研究冰片脂质体的最佳工艺。方法 :通过正交试验法 ,考察冰片的包封率这一指标。结果 :优选出试验因素 :磷脂量为 5 % (W /V) ,冰片与磷脂量之比为 1 10 (W/W ) ,胆固醇与磷脂量之比为 1 4 (W/W )。结论Objective: To study the best craft produced liposome of borneolum syntheticum. Method: To investigate the envelopment rate of borneolum syntheticum by orthogonal design. Result: experimental factors :phospholipid was 5%, borneolum syntheticum : phospholipid was 110, cholesterin : phospholipid was 14. Conclusion: The method of water-soluble medicine disgregation was suitable for producing liposome with broneolum syntheticum.

关 键 词：冰片 脂质体 制备工艺 

分 类 号：R943[医药卫生—药剂学]