益肺止咳胶囊治疗复治排菌肺结核的临床研究  

YIFEIZHIKE CAPSULES IN TREATING SECONDARY BACTERIA-DISCHARGING PULMONARY TUBERCULOSIS

作　　者：于伟 梁红文 苏振静 

机构地区：[1]临沂市胸科医院,山东临沂276002

出　　处：《临沂医学专科学校学报》2004年第6期423-425,共3页Journal of Linyi Medical College

摘　　要：目的　探讨益肺止咳胶囊对复治排菌肺结核的治疗效果。方法　将 12 8例复治排菌肺结核患者随机分为治疗组和对照组 ,每组 6 4例。对照组常规应用利福喷丁、力克肺疾、丙硫异烟胺行抗结核治疗 ;治疗组在上述治疗的基础上加用益肺止咳胶囊治疗 ,观察治疗 3个月、6个月后的痰菌转阴率、病变吸收 (空洞闭合 )率及临床症状改善情况 ,并与对照组进行比较。结果　 (1)治疗3个月后 ,治疗组痰菌阴转率为 35 .9% ,对照组为 2 3.4 % ;病变吸收 (空洞闭合 )率 5 4.7% ,对照组为 35 .9% ;临床症状改善率治疗组为 6 7.2 % ,对照组为 4 0 .6 %。 (2 )治疗 6个月后 ,治疗组痰菌阴转率为 5 7.8% ,对照组为 32 .8% ;病变吸收 (空洞闭合 )率 71.9% ,对照组为 5 3.1% ;临床症状改善率治疗组为 81.3% ,对照组为 5 3.1% ,2组比较有显著性差异 (P <0 .0 5 )。结论　益肺止咳胶囊是一种新型、有效、安全的抗结核药物。Objective To explore the curative effect of yifeizhike capsules on secondary bacteria-discharging pulmonary tuberculosis.Methods 128 cases of secondary bacteria-discharging pulmonary tuberculosis were randomly divided into the contrast group and the treatment group.The contrast group was treated with rifapentin,isoniazid aminosali-cylate and prothionamide.Yifeizhike capsules were added in the treatment group.The curative effects were compared between the two groups in terms of transformation of tubercle bacillus,pathologic absorption and other clinical symptoms.Results The rates of negative transformation,pathologic absorption and improvement in other clinical symptoms after 3-month treatment were 35.9%,54.7% and 67.2% respectively in the treatment group,while 23.4%,35.9% and 40.6% respectively in the contrast group.After six-month treatment,the rates of negative tranfcrmation,pathologic absorption and improvement in other clinical symptoms were 57.8%,71.9% and 81.3% respectively in the treatment group,while 32.8%,53.1% and 53.1% respectively in the contraqst group.There existed significant difference between the two groups (P<0.05).Conclusion Yifeizhike capsule has proven to be a safe and effective drug in treating pulmonary tuberculosis.

关 键 词：益肺止咳胶囊 肺结核 复治排菌 

分 类 号：R521[医药卫生—内科学]