牛黄解毒片的三维高效液相色谱法鉴定和指标成分的定量  

IDENTIFICATION AND DETERMINATION OF MARKER SUBSTANCES IN NIUHUANG JIEDU PlAN BY THREE DIMENSIONAL HPLC

作　　者：陈发奎[1] 郭允珍[1] 孟宪纾[1] 

机构地区：[1]沈阳药学院,沈阳110015

出　　处：《药学学报》1993年第1期57-61,共5页Acta Pharmaceutica Sinica

摘　　要：用三维高效液相色谱(three dimensional HPLC)法对中成药牛黄解毒片进行了分析。结果表明该法用于牛黄解毒片中单味中药鉴定及指标成分(marker substance)含量测定均得到较满意结果。The Chinese traditional patent medecine Niuhuang Jiedu Pian was analyzed by three dimensional HPLC. The results show that some of the Chinese herbal drugs contained in Niuhuang Jiedu Pian can be identified and the content of the marker substances can be determined. According to the results of determination, the content of baicalin, sennoside A and glycyrrhizin in Niuhuang Jiedu Pian was 4.21, 0. 59 and 1.03 (mg/tablet), respectively. The RSD was 1.6, 2.8 and 1.40%, respectively.

关 键 词：牛黄解毒片 高效液相色谱 

分 类 号：R284.1[医药卫生—中药学]