一些紫草素衍生物的园二色谱研究  

STUDIES ON CD SPECTRA OF DERIVATIVES OF SHIKONIN AND ALKANNIN

作　　者：艾克蕙[1] 晋军[1] 刘洪[2] 

机构地区：[1]四川大学化学系,测试中心,成都610064 [2]四川大学化学系

出　　处：《药学学报》1993年第4期282-285,共4页Acta Pharmaceutica Sinica

摘　　要：从四川密花滇紫草(Onosma confertum W.W.Smith)和新疆软紫草[Arnebia euchroma (Royle) Johust]的根中分到九个紫草素衍生物,其中七个为手性化合物。测定了它们的CD谱和UV谱,结果得到三对几乎完全对称的CD谱图和完全相同的UV谱图、确定了四川密花滇紫草成分均为R构型;新疆软紫草成分均为S构型。The circular dichroism (CD) and electronic absorption spectra of seven derivatives of shikonin and alkannin isolated from the roots of Onosma confertum W. W. Smith (from Sichuan) and Arnebia euchroma (Royle) Johust (from Xinjiang) were described. Each pair of CD spectra obtained was exact mirror images and the UV specra of these compounds were very similar. In comparison with the CD spectra of shikonin given in literature, the configuration of the pigments from Sichuan was assigned R and from Xinjiang were all S.

关 键 词：紫草素 圆二色谱 紫草 

分 类 号：R284.1[医药卫生—中药学]