调经孕育方药对排卵障碍性不孕者卵巢、子宫组织血流动力学参数的影响  

Study on the Effect of Tiaojing Yunyu Decoction on Hemodynamic Parameters of Uterus and Ovary of Anovulatory Infertility

作　　者：陈秋梅[1] 张树成 沈明秀[1] 

机构地区：[1]中国中医研究院西苑医院,北京100091 [2]国家计划生育委员会科学技术研究所

出　　处：《中国中医药信息杂志》2003年第12期6-9,共4页Chinese Journal of Information on Traditional Chinese Medicine

摘　　要：目的:观察调经孕育方药对排卵障碍性不孕者子宫和卵巢组织血流动力学参数的影响。方法:采用服药前后自身对照的方法对24例服用调经孕育方药的治疗组和7例服用克罗米芬的对照组进行研究。结果:排卵障碍性不孕者子宫和卵巢组织的血流动力学参数Vmax、Vmin、Tamax与正常值比较明显不足,血流阻力指标PI、RI明显增高,表明组织中供血量减少,血供不足,处于“血瘀”的亚临床状态;服用方药后,5项指标均显著改善(P<0.05～0.01),表明组织血流畅通,血流灌注充盈。结论:补肾填精养血活血的方药通过增加子宫和卵巢组织的血液供应,促进局部组织微环境和新陈代谢的改善,使组织恢复正常的生理功能,是治疗排卵障碍性不孕的有效方法。Objective: To study the Effect of Tiaojing Yunyu Decoction on hemodynamic parameters of uterus and ovary of anovulatory infertility. Methods: Among total 31 subjects who were anovulatory infertility, 24 subjects were administrated with Tiaojing Yunyu Decoction in the treated group and 7 subjects treated with Clomiphene in the control group. We observed the hemodynamic parameters before and after treatment respectively by selfcontrol. Results: In the treatment group, Vmax (maximum volume of blood supply), Vmin (minimum volume of blood supply) and Tamax (peak time), the hemodynamic parameters of uterus and ovarian, were lower than control value, the level of RI and PI were significantly increased. The results indicated that the blood perfusion volume in uterus and ovary are increased after administrated by Tiaojing Yunyu Decoction. Conclusions: The function of Tiaojing Yunyu Decoction prescription is to tonify the kidney and replenish the essence, enrich and stimulate blood circulation and it is the better choice of treating infertility by increasing the blood supply of uterus and ovary, promoting microcirculation and metabolism in these organs.

关 键 词：调经孕育方药 排卵障碍 不孕 卵巢 子宫组织 血流动力学 

分 类 号：R271.14[医药卫生—中医妇科学]