老年周围动脉硬化闭塞病与心血管疾病的关系——北京万寿路地区老年人群横断面调查  

The relation between peripheral arterial occlusive disease and cardiovascular diseases in elderly population: a cross-section study in Wanshoulu area, Beijing

作　　者：李小鹰[1] 王洁[1] 何耀[2] 范利[1] 

机构地区：[1]解放军总医院老年心内科,北京100853 [2]解放军总医院老年医学研究所

出　　处：《中华医学杂志》2003年第21期1847-1851,共5页National Medical Journal of China

基　　金：卫生部保健科研基金资助项目 ( 2 0 0 1 5 0 0 6)

摘　　要：目的　了解老年周围动脉硬化闭塞病 (PAOD)患者心血管疾病的患病率以及老年心血管高危人群PAOD的患病率。方法　以北京万寿路地区 6 0岁以上人群 2 12 4人为研究对象 ,其中男性 94 3人 ,女性 1181人 ,年龄 6 0～ 95 (6 8 5 4岁± 5 4 3岁 )。以踝肱动脉压比值 (ankle armindex ,AAI)≤ 0 9为PAOD诊断标准 ,确定和比较PAOD患者人群与非PAOD人群高血压病、高脂血症、冠心病和糖尿病的患病率。结果　 (1)本次抽样调查人群中PAOD的现患率为 15 9% (标化现患率后为16 4 % )。 (2 )老年PAOD人群中主要心血管疾病的患病率为高血压 (5 5 8% ) ,高脂血症 (5 4 3% ) ,冠心病 (4 1 0 % ) ,糖尿病 (2 5 4 % ) ,其中高血压、冠心病和糖尿病的患病率均明显高于非PAOD人群 ;PAOD人群中女性高血压的患病率和男性冠心病的患病率亦明显高于非PAOD人群 (P均 <0 0 1) ;PAOD患者心血管疾病的患病率为非PAOD人群的 1 36～ 1 6 3倍。 (3)老年心血管高危人群PAOD的患病率明显增高 ,患有 1～ 3种心血管高危因素人群PAOD的现患率分别为 17 5 5 %、2 0 33%和2 2 14 % (χ2 =7 2 4 0 8,P <0 0 5 )。结论　老年心血管高危人群PAOD的患病率明显增高 ,而PAOD患者心血管疾病的患病率亦明显高于非PAOD人群 ,其流行病学调查。Objective To investigate the prevalence of cardiovascular diseases (CVD) in the elderly with peripheral arterial occlusive disease (PAOD) and the prevalence of PAOD in the elderly with high cardiovascular factors. Methods A questionnaire survey was conducted, physical examination and electrocardiography were undertaken, blood pressure at the ankle artery and brachial artery was taken, and peripheral blood was drawn to determine the triglyceride, cholesterol, high density lipoprotein, low density lipoprotein, and fasting blood glucose among 2,124 persons aged 60～95 (mean age 68.54±5.43), 943 males and 1 183 females, in Wanshoulu area, Beijing. PAOD was defined as an ankle-arm index (AAI) ≤0.9. Results (1) The prevalence rate of PAOD was 15.91% (16.42% after being standardized). (2) The prevalence rates of essential hypertension, hyperlipidemia, coronary heart disease, and diabetes mellitus in the elderly population with PAOD were 55.8%, 54.3%, 41.0%, and 25.4% respectively, among which the prevalence rates of hypertension, coronary heart disease, and diabetes were significantly higher in the population with PAOD than in the population without PAOD (P<0.01, P<0.05, and P<0.05 respectively), The prevalence rates of hypertension in the female PAOD population and the prevalence rate of coronary heart disease in the male PAOD population were significantly higher than those in the populations without PAOD respectively (P<0.001 and P<0.01). The prevalence rate of CVD in the population with PAOD was 1.36～1.63 times higher than that in the population without PAOD. (3) The prevalence rate of PAOD was 17.55% in the elderly population with single CVD risk factor (U=3.8661, P<0.001), 20.33% in those with double risk factors, and 22.14% in those with triple factors (χ2=7.240 8, P< 0.05) respectively. Conclusion The prevalence of PAOD in Wanshoulu area is similar to that in the developed countries, suggesting that PAOD is also one of the common diseases in elderly population in China. The prevalence of CVD in the po

关 键 词：周围动脉硬化闭塞病 心血管疾病 老年人 横断面调查 流行病学 

分 类 号：R543[医药卫生—心血管疾病]