围绝经妇女雌激素与内皮素关系探讨  

Probe into the relationship between estrogen and endothelin in menopausal women

作　　者：史樱[1] 阮祥燕[1] 

机构地区：[1]首都医科大学附属北京妇产医院内分泌室,100006

出　　处：《中国妇幼保健》2005年第4期497-498,共2页Maternal and Child Health Care of China

摘　　要：　目的: 研究绝经妇女血清雌激素与内皮素关系, 探讨绝经相关疾病合理的治疗方案。方法: 选择 107例妇女进行研究, 其中绝经组 68例, 对照组 39例, 分别取静脉血测定血清促卵泡素 (FSH)、雌二醇 (E2 )、内皮素 (ET) 水平。结果:绝经妇女内皮素水平 59 5±16 0pg/ml, 明显高于育龄期 47 9±18 8pg/ml, P<0 05, 雌激素水平明显低于对照组。结论: 绝经妇女雌激素与内皮素水平呈负相关。Objective:To study the relationship between estrogen and endothelin (ET) in menopausal women and explore the suitable therapeutic scheme of the diseases concerning menopause Methods:107 women were divided into menopausal group ( n =68) and control group ( n =39) And the levels of serum follicle stimulation hormone (FSH), estradiol (E 2) and ET from venous blood were determined Results:The levels of ET in menopausal group (59 5±16 0 pg/ml) were significantly higher than that in control group (47 9±18 8 pg/ml)( P <0 05) The levels of E 2 in menopausal group were significant lower than that in control group Conclusion:There should be negative relationship between levels of ET and E 2 in menopausal women

关 键 词：内皮素 雌激素 绝经 激素替代 

分 类 号：R173[医药卫生—妇幼卫生保健]