药物涂层支架在冠状动脉长病变中的应用  

Effect of the drug-eluting stent on long coronary lesions disease

作　　者：聂增新 刘宇[2] 杨振坤[2] 倪钧[2] 胡健[2] 沈卫峰[2] 

机构地区：[1]景德镇市第一人民医院心内科 [2]上海瑞金医院心内科

出　　处：《临床心血管病杂志》2005年第2期87-89,共3页Journal of Clinical Cardiology

摘　　要：目的:评价药物涂层支架在冠状动脉长病变内(病变长度≥20 mm)的临床疗效。方法:对 50 例冠心病患者行药物涂层冠状动脉内支架治疗(56只,药物长支架组),随机选择同期50例接受普通支架治疗(52 只,普通长支架组),比较两组支架置入情况及临床事件发生率。结果: 两组手术成功率相似(100% ∶98.0%, P>0.05)。平均随访(7.6±2.1) 个月,随访率85%,药物长支架组心绞痛复发率显著低于普通长支架组(6.82% ∶19.51%,P<0.05)。结论:冠心病患者应用药物涂层支架治疗长病变临床效果优于普通支架。Objective:To evaluate the efficacy of coronary drug-eluting stent(DES) in patients with coronary artery disease(CAD). Method:From July 2003 to December 2003,50 patients were treated with long coronary drug-eluting stents(DES group).The follow-up outcomes of these patients were compared with another 50 well-matched cases who received standard uncoated stents(Control group) within the same time period.Result:Baseline clinical characteristics were similar between the two groups except that there were more diabetes mellitus in the DES group.Angiographic success rate(100%∶ 98.0%, P> 0.05) and stenting procedure were comparable in the two groups.During mean 7.6 months of follow-up, the rate of recurrent angina pectoris was significantly lower in the DES group than that in the control group( 6.82%∶ 19.51%, P< 0.05). There were no major cardiovascular events in the two groups. Conclusion:As compared with standard uncoated long coronary stent, long coronary drug-eluting stent provides better clinical efficacy.

关 键 词：冠状动脉疾病 药物涂层支架 

分 类 号：R543.3[医药卫生—心血管疾病]