A Selective Synthesis of 2-Alkylamino-5, 6, 7, 8-tetrahydro-benzothieno[2, 3-d]pyrimidin-4(3H)-ones  

作　　者：MingWuDING RuiJunXU JingXU YunFengCHEN 

机构地区：[1]KeyLaboratoryofPesticide＆ChemicalBiology,MinistryofEducation,CollegeofChemistry,CentralChinaNormalUniversity,Wuhan430079

出　　处：《Chinese Chemical Letters》2005年第2期189-192,共4页中国化学快报（英文版）

基　　金：We gratefully acknowledge financial support of this work by the National Key Project for Basic Research(2003CB114400,2003CB114406);the National Natural Science Foundation of China(Project No.20102001).

摘　　要：Alkylamino-5, 6, 7, 8-tetrahydrobenzothieno [2, 3-d] pyrimidin-4(3H)-ones 7 weresynthesized by a new selective synthetic method, which includes aza-Wittig reaction of imino-phosphorane 4 with aromatic isocynate to give carbodiimide 5 and subsequent reaction of 5 withvarious aliphatic primary amine in the presence of EtO-Na+.

关 键 词：Benzothieno[2 3-d]pyrimidin-4(3H)-ones aza-Wittig reaction iminophosphorane carbodiimide synthesis. 

分 类 号：O625.4[理学—有机化学]