栗甾酮A/B环类似物的合成研究 Ⅱ.2β,3β-二羟基-6-胆甾酮的立体选择性合成  

STUDIES ON SYNTHESIS OF A/B RING ANALOGUES OF CASTASTERONE Ⅱ.STEREOSELECTIVE SYNTHESIS OF 2β,3β-DIHYDROXY-6-CHOLESTERONE

作　　者：高碧 王植材[1] 郑其煌 许志文 

机构地区：[1]中山大学化学系,广州510275 [2]厦门大学化学系

出　　处：《应用化学》1993年第1期12-15,共4页Chinese Journal of Applied Chemistry

摘　　要：以胆甾醇为原料,经硝化、还原、消除等反应以及用I_2-AgOAc-H_2O氧化引进2β,3β-二羟基的方法,立体选择性地合成了具有栗甾酮A/B环结构单元的类似物2β,3β-二羟基-6-胆甾酮。2β, 3β-Dihydroxy-6-cholesterone, a structural analogue in A/B rings of castasterone was stereoselectively synthesized from cholesterol via nitration, reduction; elimination and oxidation reactions. The key step in the synthesis is the introduction of 2β, 3β-dihydroxy groups by oxidation with I_2-AgOAe-H_2O.

关 键 词：二羟基胆甾酮 栗甾酮 生长促进剂 

分 类 号：TQ452[化学工程—农药化工]