钇(Ⅲ)-莫西沙星配合物的荧光性质及分析应用  

The study of fluorescence properties about system of yttrium (Ⅲ)-moxifloxacin ligand and its analytical application

作　　者：王晓丽[1] 孟双明[2] 冯瑞琴[1] 赵慧春[1] 陈世稆[1] 

机构地区：[1]北京师范大学化学系,北京100875 [2]山西省雁北师范学院化学系,大同037000

出　　处：《分析试验室》2005年第1期30-32,共3页Chinese Journal of Analysis Laboratory

基　　金：国家自然科学基金项目(G1998061308);北京市自然科学基金(批准号:2022007)

摘　　要：钇(Y3+)与莫西沙星(MoxifloxacinMXFX)形成的配合物能显著地增敏莫西沙星的荧光强度,据此,建立了测定莫西沙星的新方法。该方法的检出限为8.5×10-10mol/L;莫西沙星的浓度在1.0×10-8～1.0×10-6mol/L范围内与配合物体系的荧光强度呈良好的线性关系。对1.0×10-6mol/L莫西沙星平行测定12次,RSD为1.1%。该法可用于测定尿样中的莫西沙星。对荧光增强机理作了简要的探讨。The complex formed by Yttrium (Y^(3+)) and Moxifloxacin can strengthen the relative intensity of fluorescence of Moxifloxacin evidently. As a result, a novel method for the determination of Moxifloxacin concentration has been developed. The detection limit is 8.5×10^(-10) mol/L. The relative intensity of fluorescence is linear to the concentration of Moxifloxacin in the range of 1.0×10^(-8)～1.0×10^(-6) mol/L. The relative standard deviation for the determination of 1.0×10^(-6) mol/L Moxifloxacin is 1.1% (n=12). The method has been successfully applied to the analysis of Moxifloxacin in urine. An original mechanism has been proposed to explain this phenomenon.

关 键 词：莫西沙星 钇 荧光 

分 类 号：O657.32[理学—分析化学]