新生儿黄疸巨细胞包涵体检查的临床意义  

THE CLINICAL SIGNIFICANCE OF TESTING NEONATAL JAUNDICE CYTOMEGALIC INCLUSION

作　　者：范洪[1] 侯英荣[1] 赵淑景[1] 郑小丽[1] 石海香[1] 

机构地区：[1]河北省沧州中西医结合医院,沧州061001

出　　处：《现代预防医学》2005年第1期71-72,共2页Modern Preventive Medicine

摘　　要：目的 :利用巨细胞包涵体检测方法 ,探讨巨细胞病毒感染与新生儿黄疸的关系。方法 :取患儿的尿液及其母亲的尿液、乳汁和唾液标本进行涂片 ,瑞氏染色显微镜观察巨细胞包涵体 ,找到巨细胞包涵体为阳性 ,即巨细胞病毒感染 ,未找到巨细胞包涵体为阴性。结果 :31例新生儿黄疸 ,巨细胞包涵体检查阳性 2 1例 ,阳性率为 6 7 7% ;巨细胞包涵体阳性患儿母亲的尿液、乳汁和唾液标本 ,巨细胞包涵体阳性率分别为 10 0 % (2 1/ 2 1)、 4 2 9% (9/ 2 1)、 2 3 8% (5 / 2 1) ;30例正常新生儿及其母亲的标本均为阴性。结论 :巨细胞包涵体检查可明确巨细胞病毒感染 ,确定产毒性 ,巨细胞病毒感染是新生儿黄疸的主要因素之一 ,新生儿巨细胞病毒感染与其母亲密切相关。Objective:To discuss the relationship between cytomegalovirus and neonatal jaundice by using the test method of cytomegalic inclusion.Method:The urine,latex and sputum were taken from the suffeeering newborn and their mothers then were spread on a piece of slice.Cytomegalic on inclusion were observed after Wright dyeing.Results:Thirty-one neonatal jaundice,the cytomegalic inclusion testing positive is twenty-one cases,the positive rate is 67.7%;the urine,latex and sputum sample of the mothers of cytomegalic inclusion positive suffering newborn,the positive rate is 100%(21/21),42.9%(9/21),23.8%(5/21);the samples of thirty normal newborn and their mothers are negative.Conclusion:The test of cytomegalic inclusion can definitude cytomegalovirus infection,confirm its toxic effect,cytomegalovirus infection is one of the main factors of neonatal jaundice,the newborn cytomegalovirus infection has affinity with their mothers.

关 键 词：新生儿黄疸 巨细胞病毒 巨细胞包涵体 巨细胞病毒 巨细胞包涵体 CMV 先天性 

分 类 号：R722.17[医药卫生—儿科]